Sulfasalazine and Complement factor c3 decreased - a phase IV clinical study of FDA data

Summary:

Complement factor c3 decreased is reported as a side effect among people who take Sulfasalazine (sulfasalazine), especially for people who are female, 30-39 old, have been taking the drug for 1 - 6 months also take Methotrexate,.

The phase IV clinical study analyzes which people have Complement factor c3 decreased when taking Sulfasalazine. It is created by eHealthMe based on reports of 95,646 people who have side effects when taking Sulfasalazine from the FDA, and is updated regularly.

What is Sulfasalazine?

Sulfasalazine has active ingredients of sulfasalazine. It is often used in rheumatoid arthritis. eHealthMe is studying from 96,787 Sulfasalazine users. Check the latest studies of Sulfasalazine.

What is Complement factor c3 decreased?

Complement factor c3 decreased is found to be associated with 49 drugs and 202 conditions by eHealthMe. Check the latest studies of Complement factor c3 decreased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

95,646 people reported to have side effects when taking Sulfasalazine.
Among them, 11 people (0.01%) have Complement factor c3 decreased.

Could Sulfasalazine cause Complement factor c3 decreased?

Among these 11 people:

How long have people been on Sulfasalazine when they have Complement factor c3 decreased? *

What is the gender of people who have Complement factor c3 decreased when taking Sulfasalazine? *

female: 100 %
male: 0.0 %

What is the age of people who have Complement factor c3 decreased when taking Sulfasalazine? *

What are other drugs people take besides Sulfasalazine? *

Methotrexate: 3 people, 27.27%
Xeljanz: 2 people, 18.18%
Diclofenac Sodium: 1 person, 9.09%

What are other side effects people have besides Complement factor c3 decreased? *

Vitamin B12 Deficiency: 8 people, 72.73%
Pleural Effusion (water on the lungs): 8 people, 72.73%
Vasculitis (inflammation of a blood vessel or blood vessels): 8 people, 72.73%
Glomerulonephritis Chronic (long lasting group of conditions that affect parts of the kidneys called glomeruli): 8 people, 72.73%
Gastritis (inflammation of stomach): 8 people, 72.73%
Encephalitis (inflammation of the brain): 8 people, 72.73%
Meningitis Aseptic (a condition that causes the membranes covering your brain and spinal cord to become inflamed): 8 people, 72.73%
Myelitis (infection or the inflammation of white matter or gray matter of spinal cord which is a part of central nervous system): 8 people, 72.73%
Colitis (inflammation of colon): 8 people, 72.73%
Hypercoagulation (increased tendency for clotting of the blood): 8 people, 72.73%

* Approximation only. Some reports may have incomplete information.

Do you take Sulfasalazine and have Complement factor c3 decreased?

- Check whether Complement factor c3 decreased is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sulfasalazine:

Sulfasalazine (96,787 reports)

Browse all side effects of Sulfasalazine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Complement factor c3 decreased:

Complement factor c3 decreased (49 drugs)

Browse all the conditions that are associated with Complement factor c3 decreased:

Complement factor c3 decreased (202 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sulfasalazine (the active ingredients of Sulfasalazine) and Sulfasalazine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.