Sulfasalazine and Hepatitis b - a phase IV clinical study of FDA data

Summary:

Hepatitis b is reported as a side effect among people who take Sulfasalazine (sulfasalazine), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Methotrexate, and have Ankylosing spondylitis.

The phase IV clinical study analyzes which people have Hepatitis b when taking Sulfasalazine. It is created by eHealthMe based on reports of 95,646 people who have side effects when taking Sulfasalazine from the FDA, and is updated regularly.

What is Sulfasalazine?

Sulfasalazine has active ingredients of sulfasalazine. It is often used in rheumatoid arthritis. eHealthMe is studying from 96,787 Sulfasalazine users. Check the latest studies of Sulfasalazine.

What is Hepatitis b?

Hepatitis b is found to be associated with 515 drugs and 683 conditions by eHealthMe. Check the latest studies of Hepatitis b.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

95,646 people reported to have side effects when taking Sulfasalazine.
Among them, 61 people (0.06%) have Hepatitis b.

Among these 61 people:

How long have people been on Sulfasalazine when they have Hepatitis b? *

What is the gender of people who have Hepatitis b when taking Sulfasalazine? *

female: 62.26 %
male: 37.74 %

What is the age of people who have Hepatitis b when taking Sulfasalazine? *

What are other drugs people take besides Sulfasalazine? *

Methotrexate: 13 people, 21.31%
Prednisone: 7 people, 11.48%
Humira: 6 people, 9.84%
Hydroxychloroquine Sulfate: 6 people, 9.84%
Isoniazid: 5 people, 8.20%
Alendronate Sodium: 5 people, 8.20%
Enbrel: 5 people, 8.20%
Rabeprazole: 5 people, 8.20%
Xeljanz: 5 people, 8.20%
Celebrex: 5 people, 8.20%

What are other side effects people have besides Hepatitis b? *

General Physical Health Deterioration (weak health status): 6 people, 9.84%
Oxygen Saturation Decreased: 4 people, 6.56%
Hepatitis B Dna Increased: 4 people, 6.56%
Blood Pressure Fluctuation: 4 people, 6.56%
Lung Disorder (lung disease): 4 people, 6.56%
Mixed Connective Tissue Disease (an autoimmune disease, in which the body's defence system attacks itself): 4 people, 6.56%
Hepatic Cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue): 4 people, 6.56%
Blood Pressure Diastolic Decreased: 4 people, 6.56%
Alanine Aminotransferase Increased: 4 people, 6.56%
Weakness: 4 people, 6.56%

What are the existing conditions these people have? *

Ankylosing Spondylitis (type of arthritis affecting the spine): 6 people, 9.84%
Joint Pain: 5 people, 8.20%
Pain: 4 people, 6.56%
Inflammation: 3 people, 4.92%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 3.28%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 3.28%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 3.28%
Rheumatoid Factor Positive: 1 person, 1.64%
Psoriasis (immune-mediated disease that affects the skin): 1 person, 1.64%
Osteoporosis (bones weak and more likely to break): 1 person, 1.64%

* Approximation only. Some reports may have incomplete information.

Do you take Sulfasalazine and have Hepatitis b?

- Check whether Hepatitis b is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sulfasalazine:

Sulfasalazine (96,787 reports)

Hepatitis b treatments and more:

Hepatitis b (21,088 reports)

Browse all side effects of Sulfasalazine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hepatitis b:

Hepatitis b (515 drugs)

Browse all the conditions that are associated with Hepatitis b:

Hepatitis b (683 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sulfasalazine (the active ingredients of Sulfasalazine) and Sulfasalazine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.