Sunosi and Paraesthesia - a phase IV clinical study of FDA data

Summary:

Paraesthesia is reported as a side effect among people who take Sunosi (solriamfetol), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Xywav, and have Narcolepsy.

The phase IV clinical study analyzes which people have Paraesthesia when taking Sunosi. It is created by eHealthMe based on reports of 2,920 people who have side effects when taking Sunosi from the FDA, and is updated regularly.

What is Sunosi?

Sunosi has active ingredients of solriamfetol. eHealthMe is studying from 2,936 Sunosi users. Check the latest studies of Sunosi.

What is Paraesthesia?

Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect) is found to be associated with 2,689 drugs and 3,121 conditions by eHealthMe. Check the latest studies of Paraesthesia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

2,920 people reported to have side effects when taking Sunosi.
Among them, 46 people (1.58%) have Paraesthesia.

Among these 46 people:

How long have people been on Sunosi when they have Paraesthesia? *

What is the gender of people who have Paraesthesia when taking Sunosi? *

female: 76.09 %
male: 23.91 %

What is the age of people who have Paraesthesia when taking Sunosi? *

What are other drugs people take besides Sunosi? *

What are other side effects people have besides Paraesthesia? *

Dizziness: 23 people, 50.00%
Stress And Anxiety: 21 people, 45.65%
Tremor (trembling or shaking movements in one or more parts of your body): 20 people, 43.48%
Feeling Abnormal: 17 people, 36.96%
Feeling Drunk: 16 people, 34.78%
Muscle Spasms (muscle contraction): 16 people, 34.78%
Hyperhidrosis (abnormally increased sweating): 16 people, 34.78%
Hypoaesthesia (reduced sense of touch or sensation): 15 people, 32.61%
Migraine (headache): 14 people, 30.43%
High Blood Pressure: 13 people, 28.26%

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 35 people, 76.09%
Drowsiness: 30 people, 65.22%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 22 people, 47.83%
Stress And Anxiety: 2 people, 4.35%
Muscle Spasms (muscle contraction): 2 people, 4.35%
Urinary Tract Infection: 1 person, 2.17%
Skin Wrinkling (wrinkle on skin): 1 person, 2.17%
Restless Leg Syndrome (a powerful urge to move your legs): 1 person, 2.17%
Myasthenia Gravis (a chronic condition that causes muscles to tire and weaken easily): 1 person, 2.17%
Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 1 person, 2.17%

* Approximation only. Some reports may have incomplete information.

Do you take Sunosi and have Paraesthesia?

- Check whether Paraesthesia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sunosi:

Sunosi (2,936 reports)

Paraesthesia treatments and more:

Paraesthesia (184,215 reports)

Browse all side effects of Sunosi:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Paraesthesia:

Paraesthesia (2,689 drugs)

Browse all the conditions that are associated with Paraesthesia:

Paraesthesia (3,121 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on solriamfetol (the active ingredients of Sunosi) and Sunosi (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.