Tacrolimus and Diabetes insipidus - a phase IV clinical study of FDA data

Summary:

Diabetes insipidus is reported as a side effect among people who take Tacrolimus (tacrolimus), especially for people who are male, 50-59 old, have been taking the drug for < 1 month also take Busulfex, and have Indigestion.

The phase IV clinical study analyzes which people have Diabetes insipidus when taking Tacrolimus. It is created by eHealthMe based on reports of 115,828 people who have side effects when taking Tacrolimus from the FDA, and is updated regularly.

What is Tacrolimus?

Tacrolimus has active ingredients of tacrolimus. It is often used in kidney transplant. eHealthMe is studying from 116,160 Tacrolimus users. Check the latest studies of Tacrolimus.

What is Diabetes insipidus?

Diabetes insipidus (diabetes caused by a deficiency of the pituitary hormone vasopressin, which regulates kidney function) is found to be associated with 294 drugs and 533 conditions by eHealthMe. Check the latest studies of Diabetes insipidus.

On Jul, 21, 2026

115,828 people reported to have side effects when taking Tacrolimus.
Among them, 21 people (0.02%) have Diabetes insipidus.

Could Tacrolimus cause Diabetes insipidus?

Among these 21 people:

How long have people been on Tacrolimus when they have Diabetes insipidus? *

What is the gender of people who have Diabetes insipidus when taking Tacrolimus? *

female: 23.81 %
male: 76.19 %

What is the age of people who have Diabetes insipidus when taking Tacrolimus? *

What are other drugs people take besides Tacrolimus? *

Busulfex: 7 people, 33.33%
Melphalan: 6 people, 28.57%
Vitamin B6: 2 people, 9.52%
Pantoprazole: 2 people, 9.52%
Fludarabine Phosphate: 2 people, 9.52%
Myfortic: 2 people, 9.52%
Norvasc: 2 people, 9.52%
Pancreatin: 2 people, 9.52%
Imipenem And Cilastatin: 2 people, 9.52%
Daunorubicin Hydrochloride: 1 person, 4.76%

What are other side effects people have besides Diabetes insipidus? *

Acute Graft Versus Host Disease (acute complication following an allogeneic tissue/blood transplant): 5 people, 23.81%
Nausea (feeling of having an urge to vomit): 5 people, 23.81%
Weight Increased: 4 people, 19.05%
Constipation: 4 people, 19.05%
Nausea And Vomiting: 4 people, 19.05%
Stomatitis (inflammation of mucous membrane of mouth): 4 people, 19.05%
Asthma: 3 people, 14.29%
Malaise (a feeling of general discomfort or uneasiness): 3 people, 14.29%
Myocarditis (inflammation of heart muscle myocardium): 3 people, 14.29%
Hypoalbuminaemia (levels of albumin in blood serum are abnormally low): 3 people, 14.29%

What are the existing conditions these people have? *

Urine Output Increased: 2 people, 9.52%
High Blood Pressure: 2 people, 9.52%
Bone Marrow Conditioning Regimen: 2 people, 9.52%
Cardiovascular Insufficiency (inadequate functioning of heart): 2 people, 9.52%
Drug Level Increased: 2 people, 9.52%
Fluid Imbalance (imbalance of fluid in body in intake and fluid lost): 2 people, 9.52%
Urine Analysis Abnormal: 2 people, 9.52%
Acute Graft Versus Host Disease (acute complication following an allogeneic tissue/blood transplant): 2 people, 9.52%
Hypocalcaemia (levels of calcium in blood serum are abnormally low): 2 people, 9.52%
Indigestion: 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

Do you take Tacrolimus and have Diabetes insipidus?

- Check whether Diabetes insipidus is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tacrolimus:

Tacrolimus (116,160 reports)

Browse all side effects of Tacrolimus:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Diabetes insipidus:

Diabetes insipidus (294 drugs)

Browse all the conditions that are associated with Diabetes insipidus:

Diabetes insipidus (533 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on tacrolimus (the active ingredients of Tacrolimus) and Tacrolimus (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.