Tacrolimus and Folate deficiency - a phase IV clinical study of FDA data

Summary:

Folate deficiency is reported as a side effect among people who take Tacrolimus (tacrolimus), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Mycophenolate Mofetil, and have Nephrogenic anaemia.

The phase IV clinical study analyzes which people have Folate deficiency when taking Tacrolimus. It is created by eHealthMe based on reports of 115,828 people who have side effects when taking Tacrolimus from the FDA, and is updated regularly.

What is Tacrolimus?

Tacrolimus has active ingredients of tacrolimus. It is often used in kidney transplant. eHealthMe is studying from 116,160 Tacrolimus users. Check the latest studies of Tacrolimus.

What is Folate deficiency?

Folate deficiency (lack of folic acid) is found to be associated with 227 drugs and 403 conditions by eHealthMe. Check the latest studies of Folate deficiency.

On Jul, 06, 2026

115,828 people reported to have side effects when taking Tacrolimus.
Among them, 26 people (0.02%) have Folate deficiency.

Could Tacrolimus cause Folate deficiency?

Among these 26 people:

How long have people been on Tacrolimus when they have Folate deficiency? *

What is the gender of people who have Folate deficiency when taking Tacrolimus? *

female: 80.77 %
male: 19.23 %

What is the age of people who have Folate deficiency when taking Tacrolimus? *

What are other drugs people take besides Tacrolimus? *

Mycophenolate Mofetil: 13 people, 50.00%
Eprex: 9 people, 34.62%
Mesalamine: 6 people, 23.08%
Azathioprine: 6 people, 23.08%
Cyclosporine: 6 people, 23.08%
Prednisolone: 6 people, 23.08%
Mitoxantrone: 4 people, 15.38%
Nelarabine: 4 people, 15.38%
Furosemide: 2 people, 7.69%
Flonase: 2 people, 7.69%

What are other side effects people have besides Folate deficiency? *

Drug Ineffective: 10 people, 38.46%
Hyperparathyroidism (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium): 10 people, 38.46%
Nausea And Vomiting: 7 people, 26.92%
Anaemia (lack of blood): 7 people, 26.92%
Dizziness: 7 people, 26.92%
Papilloedema (optic disc swelling): 6 people, 23.08%
Rickets (softening of bones): 6 people, 23.08%
Drug Intolerance (drug sensitivity): 6 people, 23.08%
Drug Hypersensitivity: 6 people, 23.08%
Pancreatitis (inflammation of pancreas): 6 people, 23.08%

What are the existing conditions these people have? *

Nephrogenic Anaemia (anaemia due to kidney disease): 10 people, 38.46%
Pancreatitis (inflammation of pancreas): 5 people, 19.23%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 4 people, 15.38%
T-Cell Type Acute Leukaemia (a form of cancer of the white blood cells): 2 people, 7.69%
Leukaemia Recurrent (repeat cancer of bone marrow or blood cells): 2 people, 7.69%
Hyperparathyroidism Secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary): 2 people, 7.69%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 2 people, 7.69%
Psoriasis (immune-mediated disease that affects the skin): 1 person, 3.85%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 3.85%

* Approximation only. Some reports may have incomplete information.

Do you take Tacrolimus and have Folate deficiency?

- Check whether Folate deficiency is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tacrolimus:

Tacrolimus (116,160 reports)

Browse all side effects of Tacrolimus:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Folate deficiency:

Folate deficiency (227 drugs)

Browse all the conditions that are associated with Folate deficiency:

Folate deficiency (403 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on tacrolimus (the active ingredients of Tacrolimus) and Tacrolimus (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.