Tecfidera and Seizure like phenomena - a phase IV clinical study of FDA data

Summary:

Seizure like phenomena is reported as a side effect among people who take Tecfidera (dimethyl fumarate), especially for people who are female, 50-59 old, have been taking the drug for 2 - 5 years also take Copaxone, and have Suicide attempt.

The phase IV clinical study analyzes which people have Seizure like phenomena when taking Tecfidera. It is created by eHealthMe based on reports of 129,391 people who have side effects when taking Tecfidera from the FDA, and is updated regularly.

What is Tecfidera?

Tecfidera has active ingredients of dimethyl fumarate. It is often used in multiple sclerosis. eHealthMe is studying from 129,627 Tecfidera users. Check the latest studies of Tecfidera.

What is Seizure like phenomena?

Seizure like phenomena (a variety of medical conditions may produce sudden episodes which have some similarities to epileptic seizures) is found to be associated with 204 drugs and 341 conditions by eHealthMe. Check the latest studies of Seizure like phenomena.

On Jul, 09, 2026

129,391 people reported to have side effects when taking Tecfidera.
Among them, 27 people (0.02%) have Seizure like phenomena.

Could Tecfidera cause Seizure like phenomena?

Among these 27 people:

How long have people been on Tecfidera when they have Seizure like phenomena? *

What is the gender of people who have Seizure like phenomena when taking Tecfidera? *

female: 74.07 %
male: 25.93 %

What is the age of people who have Seizure like phenomena when taking Tecfidera? *

What are other drugs people take besides Tecfidera? *

What are other side effects people have besides Seizure like phenomena? *

Memory Loss: 6 people, 22.22%
Headache (pain in head): 5 people, 18.52%
Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 4 people, 14.81%
Skin Blushing/flushing (a sudden reddening of the face, neck): 4 people, 14.81%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 4 people, 14.81%
Muscle Spasms (muscle contraction): 3 people, 11.11%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 3 people, 11.11%
Irritability: 3 people, 11.11%
Bipolar Disorder (mood disorder): 3 people, 11.11%
Hot Flush (sudden feelings of heat): 3 people, 11.11%

What are the existing conditions these people have? *

Suicide Attempt: 3 people, 11.11%
Gait Disturbance: 2 people, 7.41%
Neuralgia (pain in one or more nerves): 1 person, 3.70%
Muscle Spasms (muscle contraction): 1 person, 3.70%

* Approximation only. Some reports may have incomplete information.

Do you take Tecfidera and have Seizure like phenomena?

- Check whether Seizure like phenomena is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tecfidera:

Tecfidera (129,627 reports)

Browse all side effects of Tecfidera:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Seizure like phenomena:

Seizure like phenomena (204 drugs)

Browse all the conditions that are associated with Seizure like phenomena:

Seizure like phenomena (341 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on dimethyl fumarate (the active ingredients of Tecfidera) and Tecfidera (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.