Tpn and Thrombocytopenia - a phase IV clinical study of FDA data

Summary:

Thrombocytopenia is reported as a side effect among people who take Tpn (niacinamide; pyridoxine hydrochloride; tyrosine), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Vancomycin, and have Pain.

The phase IV clinical study analyzes which people have Thrombocytopenia when taking Tpn. It is created by eHealthMe based on reports of 1,568 people who have side effects when taking Tpn from the FDA, and is updated regularly.

What is Tpn?

Tpn has active ingredients of niacinamide; pyridoxine hydrochloride; tyrosine. eHealthMe is studying from 1,581 Tpn users. Check the latest studies of Tpn.

What is Thrombocytopenia?

Thrombocytopenia (decrease of platelets in blood) is found to be associated with 2,791 drugs and 4,873 conditions by eHealthMe. Check the latest studies of Thrombocytopenia.

On Jul, 28, 2026

1,568 people reported to have side effects when taking Tpn.
Among them, 42 people (2.68%) have Thrombocytopenia.

Among these 42 people:

How long have people been on Tpn when they have Thrombocytopenia? *

What is the gender of people who have Thrombocytopenia when taking Tpn? *

female: 55.26 %
male: 44.74 %

What is the age of people who have Thrombocytopenia when taking Tpn? *

What are other drugs people take besides Tpn? *

What are other side effects people have besides Thrombocytopenia? *

White Blood Cell Count Decreased: 13 people, 30.95%
Mental Status Changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation): 9 people, 21.43%
Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 8 people, 19.05%
Weakness: 8 people, 19.05%
Sepsis (a severe blood infection that can lead to organ failure and death): 8 people, 19.05%
Cytokine Release Syndrome (immediate complication occurring with the use of anti-t cell antibody infusions): 7 people, 16.67%
Fever: 7 people, 16.67%
Fluid Overload (too much fluid in the blood): 7 people, 16.67%
Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system): 7 people, 16.67%
Pulmonary Oedema (fluid accumulation in the lungs): 7 people, 16.67%

What are the existing conditions these people have? *

Pain: 14 people, 33.33%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 9 people, 21.43%
Nausea (feeling of having an urge to vomit): 9 people, 21.43%
Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood): 7 people, 16.67%
Diarrhea: 6 people, 14.29%
Hypotension (abnormally low blood pressure): 5 people, 11.90%
Febrile Neutropenia (fever with reduced white blood cells): 5 people, 11.90%
High Blood Pressure: 5 people, 11.90%
Hyperlipidaemia (presence of excess lipids in the blood): 5 people, 11.90%
Hypertriglyceridaemia (excess of triglycerides in the blood): 5 people, 11.90%

* Approximation only. Some reports may have incomplete information.

Do you take Tpn and have Thrombocytopenia?

- Check whether Thrombocytopenia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tpn:

Tpn (1,581 reports)

Thrombocytopenia treatments and more:

Thrombocytopenia (285,083 reports)

How severe was Thrombocytopenia and when was it recovered:

Thrombocytopenia in Tpn

Expand to all the drugs that have ingredients of niacinamide; pyridoxine hydrochloride; tyrosine:

Thrombocytopenia and drugs with ingredients of niacinamide; pyridoxine hydrochloride; tyrosine (60 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tpn:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Thrombocytopenia:

Thrombocytopenia (2,791 drugs)

Browse all the conditions that are associated with Thrombocytopenia:

Thrombocytopenia (4,873 conditions)

Related publications that referenced our studies

YavasogluI, I., TurgutkayaII, A., & BolamanIII, Z., "Chlorella-induced thrombocytopenia", DATA, 2018 Jan .
Rasmy A, Rahal M, Kisana M, Ahmad S, Salah A, "Morphine induced thrombocytopenia: A case report", Journal of Case Reports and Images in Oncology, 2015 Dec .
Onder H, Arsava EM, Arat A, Topcuoglu MA, "Acute middle cerebral artery occlusion treated by thrombectomy in a patient with myelodysplastic syndrome and severe thrombocytopenia", Journal of vascular and interventional neurology, 2015 Jan .
YavasogluI, I., TurgutkayaII, A., & BolamanIII, Z., "Chlorella-induced thrombocytopenia", DATA, 2018 Jan .
Rasmy A, Rahal M, Kisana M, Ahmad S, Salah A, "Morphine induced thrombocytopenia: A case report", Journal of Case Reports and Images in Oncology, 2015 Dec .
Onder H, Arsava EM, Arat A, Topcuoglu MA, "Acute middle cerebral artery occlusion treated by thrombectomy in a patient with myelodysplastic syndrome and severe thrombocytopenia", Journal of vascular and interventional neurology, 2015 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on niacinamide; pyridoxine hydrochloride; tyrosine (the active ingredients of Tpn) and Tpn (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.