Tpn and Vitamin d decreased - a phase IV clinical study of FDA data

Summary:

Vitamin d decreased is reported as a side effect among people who take Tpn (niacinamide; pyridoxine hydrochloride; tyrosine), especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years also take Vitamin D, and have Short-bowel syndrome.

The phase IV clinical study analyzes which people have Vitamin d decreased when taking Tpn. It is created by eHealthMe based on reports of 1,568 people who have side effects when taking Tpn from the FDA, and is updated regularly.

What is Tpn?

Tpn has active ingredients of niacinamide; pyridoxine hydrochloride; tyrosine. eHealthMe is studying from 1,581 Tpn users. Check the latest studies of Tpn.

What is Vitamin d decreased?

Vitamin d decreased is found to be associated with 800 drugs and 893 conditions by eHealthMe. Check the latest studies of Vitamin d decreased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 15, 2026

1,568 people reported to have side effects when taking Tpn.
Among them, 22 people (1.4%) have Vitamin d decreased.

Among these 22 people:

How long have people been on Tpn when they have Vitamin d decreased? *

What is the gender of people who have Vitamin d decreased when taking Tpn? *

female: 95.24 %
male: 4.76 %

What is the age of people who have Vitamin d decreased when taking Tpn? *

What are other drugs people take besides Tpn? *

What are other side effects people have besides Vitamin d decreased? *

Fatigue (feeling of tiredness): 19 people, 86.36%
Diarrhea: 16 people, 72.73%
Nausea (feeling of having an urge to vomit): 13 people, 59.09%
Pain In Extremity: 13 people, 59.09%
Abdominal Pain Upper: 12 people, 54.55%
Faeces Discolored: 12 people, 54.55%
Abdominal Pain: 12 people, 54.55%
Weight Increased: 11 people, 50.00%
Flatulence (flatus expelled through the anus): 11 people, 50.00%
Urinary Tract Infection: 11 people, 50.00%

What are the existing conditions these people have? *

Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 18 people, 81.82%
Fungal Infection: 8 people, 36.36%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 8 people, 36.36%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 8 people, 36.36%
Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve): 6 people, 27.27%
Malignant Melanoma (skin cancer rises from melancytes): 2 people, 9.09%
Adverse Event: 2 people, 9.09%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 4.55%
Renal Tubular Acidosis (medical condition that involves an accumulation of acid in the body due to a failure of the kidneys): 1 person, 4.55%
Flatulence (flatus expelled through the anus): 1 person, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Tpn and have Vitamin d decreased?

- Check whether Vitamin d decreased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tpn:

Tpn (1,581 reports)

Vitamin d decreased treatments and more:

Vitamin d decreased (13,944 reports)

How severe was Vitamin d decreased and when was it recovered:

Vitamin d decreased in Tpn

Expand to all the drugs that have ingredients of niacinamide; pyridoxine hydrochloride; tyrosine:

Vitamin d decreased and drugs with ingredients of niacinamide; pyridoxine hydrochloride; tyrosine (27 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tpn:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Vitamin d decreased:

Vitamin d decreased (800 drugs)

Browse all the conditions that are associated with Vitamin d decreased:

Vitamin d decreased (893 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on niacinamide; pyridoxine hydrochloride; tyrosine (the active ingredients of Tpn) and Tpn (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.