Trintellix and Wheezing - a phase IV clinical study of FDA data

Summary:

Wheezing is reported as a side effect among people who take Trintellix (vortioxetine hydrobromide), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Lyrica, and have Narcolepsy.

The phase IV clinical study analyzes which people have Wheezing when taking Trintellix. It is created by eHealthMe based on reports of 12,454 people who have side effects when taking Trintellix from the FDA, and is updated regularly.

What is Trintellix?

Trintellix has active ingredients of vortioxetine hydrobromide. It is often used in depression. eHealthMe is studying from 13,067 Trintellix users. Check the latest studies of Trintellix.

What is Wheezing?

Wheezing (a high-pitched whistling sound made while you breath) is found to be associated with 1,798 drugs and 2,211 conditions by eHealthMe. Check the latest studies of Wheezing.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

12,454 people reported to have side effects when taking Trintellix.
Among them, 19 people (0.15%) have Wheezing.

Among these 19 people:

How long have people been on Trintellix when they have Wheezing? *

What is the gender of people who have Wheezing when taking Trintellix? *

female: 72.22 %
male: 27.78 %

What is the age of people who have Wheezing when taking Trintellix? *

What are other drugs people take besides Trintellix? *

What are other side effects people have besides Wheezing? *

Dyspnea (difficult or laboured breathing): 7 people, 36.84%
Headache (pain in head): 5 people, 26.32%
Diarrhea: 5 people, 26.32%
Acute Upper Airway Obstruction (blockage occurs in the upper airway): 4 people, 21.05%
Nasal Discomfort: 4 people, 21.05%
Chest Pain: 4 people, 21.05%
Burning Sensation: 4 people, 21.05%
Respiratory Tract Congestion (blockage on respiratory system): 4 people, 21.05%
Blood Pressure Abnormal: 4 people, 21.05%
Dry Mouth: 4 people, 21.05%

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 31.58%
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 3 people, 15.79%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 3 people, 15.79%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 10.53%
Migraine (headache): 2 people, 10.53%
Tardive Dyskinesia (a disorder that involves involuntary movements): 1 person, 5.26%
High Blood Cholesterol: 1 person, 5.26%
Back Pain: 1 person, 5.26%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 5.26%
Enteritis (inflammation of the small intestine): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Trintellix and have Wheezing?

- Check whether Wheezing is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Trintellix:

Trintellix (13,067 reports)

Wheezing treatments and more:

Wheezing (77,221 reports)

Browse all side effects of Trintellix:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Wheezing:

Wheezing (1,798 drugs)

Browse all the conditions that are associated with Wheezing:

Wheezing (2,211 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on vortioxetine hydrobromide (the active ingredients of Trintellix) and Trintellix (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.