Trodelvy and Pain exacerbated - a phase IV clinical study of FDA data

Summary:

Pain exacerbated is reported as a side effect among people who take Trodelvy (sacituzumab govitecan-hziy), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Acetaminophen, and have Atrial fibrillation/flutter.

The phase IV clinical study analyzes which people have Pain exacerbated when taking Trodelvy. It is created by eHealthMe based on reports of 1,370 people who have side effects when taking Trodelvy from the FDA, and is updated regularly.

What is Trodelvy?

Trodelvy has active ingredients of sacituzumab govitecan-hziy. eHealthMe is studying from 1,370 Trodelvy users. Check the latest studies of Trodelvy.

What is Pain exacerbated?

Pain exacerbated is found to be associated with 3,977 drugs and 3,033 conditions by eHealthMe. Check the latest studies of Pain exacerbated.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 28, 2026

1,370 people reported to have side effects when taking Trodelvy.
Among them, 23 people (1.68%) have Pain exacerbated.

Among these 23 people:

How long have people been on Trodelvy when they have Pain exacerbated? *

What is the gender of people who have Pain exacerbated when taking Trodelvy? *

female: 95.45 %
male: 4.55 %

What is the age of people who have Pain exacerbated when taking Trodelvy? *

What are other drugs people take besides Trodelvy? *

Acetaminophen: 6 people, 26.09%
Dexamethasone: 5 people, 21.74%
Tylenol: 5 people, 21.74%
Diphenhydramine Hydrochloride: 4 people, 17.39%
Capecitabine: 3 people, 13.04%
Xeloda: 3 people, 13.04%
Doxorubicin Hydrochloride: 3 people, 13.04%
Pantoprazole: 2 people, 8.70%
Famotidine: 2 people, 8.70%
Gemzar: 2 people, 8.70%

What are other side effects people have besides Pain exacerbated? *

Diarrhea: 11 people, 47.83%
Fatigue (feeling of tiredness): 10 people, 43.48%
Constipation: 10 people, 43.48%
Drowsiness: 7 people, 30.43%
Hypotension (abnormally low blood pressure): 6 people, 26.09%
Weight Increased: 5 people, 21.74%
Rashes (redness): 5 people, 21.74%
Weight Decreased: 5 people, 21.74%
Abdominal Pain: 5 people, 21.74%
Abdominal Pain Upper: 5 people, 21.74%

What are the existing conditions these people have? *

Transitional Cell Carcinoma Metastatic (cancer of urinary inner most layer spreads to other part of body): 1 person, 4.35%
Transitional Cell Carcinoma (cancer tumour inner most layer of urinary system): 1 person, 4.35%
Rashes (redness): 1 person, 4.35%
Neoplasm Malignant (cancer tumour): 1 person, 4.35%
Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough): 1 person, 4.35%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 1 person, 4.35%
Constipation: 1 person, 4.35%
Brain Oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain): 1 person, 4.35%
Blood Magnesium Decreased: 1 person, 4.35%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 4.35%

* Approximation only. Some reports may have incomplete information.

Do you take Trodelvy and have Pain exacerbated?

- Check whether Pain exacerbated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Trodelvy:

Trodelvy (1,370 reports)

Browse all side effects of Trodelvy:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pain exacerbated:

Pain exacerbated (3,977 drugs)

Browse all the conditions that are associated with Pain exacerbated:

Pain exacerbated (3,033 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sacituzumab govitecan-hziy (the active ingredients of Trodelvy) and Trodelvy (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.