Tylenol w/ codeine and Left ventricular dysfunction - a phase IV clinical study of FDA data

Summary:

Left ventricular dysfunction is reported as a side effect among people who take Tylenol w/ codeine (acetaminophen; codeine phosphate), especially for people who are male, 60+ old, also take Oxycontin, and have Metastases to bone.

The phase IV clinical study analyzes which people have Left ventricular dysfunction when taking Tylenol w/ codeine. It is created by eHealthMe based on reports of 7,307 people who have side effects when taking Tylenol w/ codeine from the FDA, and is updated regularly.

What is Tylenol w/ codeine?

Tylenol w/ codeine has active ingredients of acetaminophen; codeine phosphate. It is often used in pain. eHealthMe is studying from 8,106 Tylenol w/ codeine users. Check the latest studies of Tylenol w/ codeine.

What is Left ventricular dysfunction?

Left ventricular dysfunction is found to be associated with 922 drugs and 788 conditions by eHealthMe. Check the latest studies of Left ventricular dysfunction.

On Jan, 21, 2026

7,307 people reported to have side effects when taking Tylenol w/ codeine.
Among them, 19 people (0.26%) have Left ventricular dysfunction.

Could Tylenol w/ codeine cause Left ventricular dysfunction?

Among these 19 people:

What is the gender of people who have Left ventricular dysfunction when taking Tylenol w/ codeine? *

female: 5.26 %
male: 94.74 %

What is the age of people who have Left ventricular dysfunction when taking Tylenol w/ codeine? *

What are other drugs people take besides Tylenol w/ codeine? *

Dexamethasone: 15 people, 78.95%
Nystatin: 15 people, 78.95%
Chlorhexidine Gluconate: 15 people, 78.95%
Lactulose: 15 people, 78.95%
Zometa: 15 people, 78.95%
Oxycontin: 15 people, 78.95%
Senna: 14 people, 73.68%
Temazepam: 14 people, 73.68%
Plavix: 12 people, 63.16%
Percocet: 11 people, 57.89%

What are other side effects people have besides Left ventricular dysfunction? *

Intervertebral Disc Protrusion (spinal disc protrusion): 16 people, 84.21%
Arrhythmias (irregular heartbeat): 16 people, 84.21%
Fall: 15 people, 78.95%
Bone Disorder: 15 people, 78.95%
Infection: 15 people, 78.95%
Osteonecrosis Of Jaw (death of bone of jaw): 15 people, 78.95%
Stress And Anxiety: 15 people, 78.95%
Spinal Cord Compression: 13 people, 68.42%
Head Injury: 10 people, 52.63%
Fainting (loss of consciousness and postural tone): 10 people, 52.63%

What are the existing conditions these people have? *

Metastases To Bone (cancer spreads to bone): 15 people, 78.95%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 10 people, 52.63%
Multiple Myeloma (cancer of the plasma cells): 5 people, 26.32%
Essential Hypertension (primary hypertension): 2 people, 10.53%
Small Cell Lung Cancer Metastatic (lung cancer spreads to other body parts): 1 person, 5.26%
Non-Small Cell Lung Cancer Metastatic (type of epithelial lung cancer spreads to other parts): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Tylenol w/ codeine and have Left ventricular dysfunction?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tylenol w/ codeine:

Tylenol w/ codeine (8,106 reports)

Left ventricular dysfunction treatments and more:

Left ventricular dysfunction (8,945 reports)

How severe was Left ventricular dysfunction and when was it recovered:

Left ventricular dysfunction in Tylenol w/ codeine

Expand to all the drugs that have ingredients of acetaminophen; codeine phosphate:

Left ventricular dysfunction and drugs with ingredients of acetaminophen; codeine phosphate (42 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tylenol w/ codeine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Left ventricular dysfunction:

Left ventricular dysfunction (922 drugs)

Browse all the conditions that are associated with Left ventricular dysfunction:

Left ventricular dysfunction (788 conditions)

Drugs similar to Tylenol w/ codeine and Left ventricular dysfunction :

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; codeine phosphate (the active ingredients of Tylenol w/ codeine) and Tylenol w/ codeine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.