Valium and Secondary progressive multiple sclerosis - a phase IV clinical study of FDA data

Summary:

Secondary progressive multiple sclerosis is reported as a side effect among people who take Valium (diazepam), especially for people who are female, 60+ old, also take Ampyra, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Secondary progressive multiple sclerosis when taking Valium. It is created by eHealthMe based on reports of 45,658 people who have side effects when taking Valium from the FDA, and is updated regularly.

What is Valium?

Valium has active ingredients of diazepam. It is often used in stress and anxiety. eHealthMe is studying from 48,647 Valium users. Check the latest studies of Valium.

What is Secondary progressive multiple sclerosis?

Secondary progressive multiple sclerosis (a stage of ms which comes after relapsing remitting ms in many cases) is found to be associated with 139 drugs and 131 conditions by eHealthMe. Check the latest studies of Secondary progressive multiple sclerosis.



On Jul, 10, 2026

45,658 people reported to have side effects when taking Valium.
Among them, 19 people (0.04%) have Secondary progressive multiple sclerosis.

Could Valium cause Secondary progressive multiple sclerosis?

Among these 19 people:

What is the gender of people who have Secondary progressive multiple sclerosis when taking Valium? *

  • female: 78.95 %
  • male: 21.05 %

What is the age of people who have Secondary progressive multiple sclerosis when taking Valium? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 14.29 %
  • 40-49: 14.29 %
  • 50-59: 28.57 %
  • 60+: 42.86 %

What are other drugs people take besides Valium? *

  1. Ampyra: 6 people, 31.58%
  2. Tysabri: 5 people, 26.32%
  3. Vitamin D: 5 people, 26.32%
  4. Provigil: 4 people, 21.05%
  5. Vitamin D3: 4 people, 21.05%
  6. Lyrica: 3 people, 15.79%
  7. Cymbalta: 3 people, 15.79%
  8. Norco: 3 people, 15.79%
  9. Calcium: 3 people, 15.79%
  10. Tecfidera: 3 people, 15.79%

What are other side effects people have besides Secondary progressive multiple sclerosis? *

  1. Fall: 6 people, 31.58%
  2. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 31.58%
  3. Fatigue (feeling of tiredness): 5 people, 26.32%
  4. Depression: 5 people, 26.32%
  5. Drug Ineffective: 5 people, 26.32%
  6. Multiple Sclerosis Relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 21.05%
  7. Weakness: 4 people, 21.05%
  8. Urinary Tract Infection: 4 people, 21.05%
  9. Cognitive Disorder (mental health disorders affects learning, memory, perception, and problem solving): 3 people, 15.79%
  10. Memory Loss: 3 people, 15.79%

What are the existing conditions these people have? *

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 10 people, 52.63%
  2. Gait Disturbance: 4 people, 21.05%
  3. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 2 people, 10.53%
  4. Pain: 2 people, 10.53%
  5. Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 2 people, 10.53%
  6. Fatigue (feeling of tiredness): 2 people, 10.53%
  7. Urinary Retention (the inability to completely or partially empty the bladder): 1 person, 5.26%
  8. High Blood Cholesterol: 1 person, 5.26%
  9. Depression: 1 person, 5.26%
  10. Dry Eyes (lack of adequate tears): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Valium and have Secondary progressive multiple sclerosis?

- Check whether Secondary progressive multiple sclerosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Valium:

Secondary progressive multiple sclerosis treatments and more:

How severe was Secondary progressive multiple sclerosis and when was it recovered:

Expand to all the drugs that have ingredients of diazepam:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Valium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Secondary progressive multiple sclerosis:

Browse all the conditions that are associated with Secondary progressive multiple sclerosis:


How the study uses the data?

The study uses data from the FDA. It is based on diazepam (the active ingredients of Valium) and Valium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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