Vesicare and Local swelling - a phase IV clinical study of FDA data

Summary:

Local swelling is reported as a side effect among people who take Vesicare (solifenacin succinate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Aspirin, and have Hypertonic bladder.

The phase IV clinical study analyzes which people have Local swelling when taking Vesicare. It is created by eHealthMe based on reports of 29,875 people who have side effects when taking Vesicare from the FDA, and is updated regularly.

What is Vesicare?

Vesicare has active ingredients of solifenacin succinate. It is often used in urge incontinence. eHealthMe is studying from 30,655 Vesicare users. Check the latest studies of Vesicare.

What is Local swelling?

Local swelling (swelling at the site of some application of substance or injury) is found to be associated with 1,008 drugs and 1,405 conditions by eHealthMe. Check the latest studies of Local swelling.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

29,875 people reported to have side effects when taking Vesicare.
Among them, 50 people (0.17%) have Local swelling.

Among these 50 people:

How long have people been on Vesicare when they have Local swelling? *

What is the gender of people who have Local swelling when taking Vesicare? *

female: 75.51 %
male: 24.49 %

What is the age of people who have Local swelling when taking Vesicare? *

What are other drugs people take besides Vesicare? *

What are other side effects people have besides Local swelling? *

Pain In Extremity: 10 people, 20.00%
Joint Pain: 8 people, 16.00%
Gait Disturbance: 8 people, 16.00%
Rashes (redness): 8 people, 16.00%
Constipation: 6 people, 12.00%
Joint Swelling: 6 people, 12.00%
Abdominal Pain Upper: 5 people, 10.00%
Headache (pain in head): 5 people, 10.00%
Insomnia (sleeplessness): 4 people, 8.00%
Oropharyngeal Pain: 4 people, 8.00%

What are the existing conditions these people have? *

Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 9 people, 18.00%
High Blood Pressure: 4 people, 8.00%
Micturition Urgency (urgency to pass the urine): 4 people, 8.00%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 8.00%
Joint Pain: 3 people, 6.00%
High Blood Cholesterol: 3 people, 6.00%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 6.00%
Bone Disorder: 2 people, 4.00%
Neuropathy Peripheral (surface nerve damage): 2 people, 4.00%
Depression: 2 people, 4.00%

* Approximation only. Some reports may have incomplete information.

Do you take Vesicare and have Local swelling?

- Check whether Local swelling is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vesicare:

Vesicare (30,655 reports)

Local swelling treatments and more:

Local swelling (21,122 reports)

Browse all side effects of Vesicare:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Local swelling:

Local swelling (1,008 drugs)

Browse all the conditions that are associated with Local swelling:

Local swelling (1,405 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on solifenacin succinate (the active ingredients of Vesicare) and Vesicare (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.