Vesicare and Sick sinus syndrome - a phase IV clinical study of FDA data

Summary:

Sick sinus syndrome is reported as a side effect among people who take Vesicare (solifenacin succinate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Micardis, and have Hypertonic bladder.

The phase IV clinical study analyzes which people have Sick sinus syndrome when taking Vesicare. It is created by eHealthMe based on reports of 29,875 people who have side effects when taking Vesicare from the FDA, and is updated regularly.

What is Vesicare?

Vesicare has active ingredients of solifenacin succinate. It is often used in urge incontinence. eHealthMe is studying from 30,656 Vesicare users. Check the latest studies of Vesicare.

What is Sick sinus syndrome?

Sick sinus syndrome (a collection of heart rhythm disorders) is found to be associated with 580 drugs and 842 conditions by eHealthMe. Check the latest studies of Sick sinus syndrome.

On Jul, 07, 2026

29,875 people reported to have side effects when taking Vesicare.
Among them, 23 people (0.08%) have Sick sinus syndrome.

Could Vesicare cause Sick sinus syndrome?

Among these 23 people:

How long have people been on Vesicare when they have Sick sinus syndrome? *

What is the gender of people who have Sick sinus syndrome when taking Vesicare? *

female: 65.22 %
male: 34.78 %

What is the age of people who have Sick sinus syndrome when taking Vesicare? *

What are other drugs people take besides Vesicare? *

What are other side effects people have besides Sick sinus syndrome? *

Hyperkalemia (damage to or disease of the kidney): 7 people, 30.43%
Renal Impairment (severely reduced kidney function): 4 people, 17.39%
Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 4 people, 17.39%
Dehydration (dryness resulting from the removal of water): 3 people, 13.04%
Loss Of Consciousness: 3 people, 13.04%
Electrolyte Imbalance: 3 people, 13.04%
Wheezing (a high-pitched whistling sound made while you breath): 1 person, 4.35%
Abdominal Pain Lower: 1 person, 4.35%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 4.35%
Bradycardia (abnormally slow heart action): 1 person, 4.35%

What are the existing conditions these people have? *

Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 17 people, 73.91%
High Blood Pressure: 14 people, 60.87%
Cardiac Failure Chronic: 6 people, 26.09%
Diabetes: 3 people, 13.04%
Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 2 people, 8.70%
Osteoporosis (bones weak and more likely to break): 2 people, 8.70%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 2 people, 8.70%
Cerebral Infarction (less blood supply to brain resulting tissue damage): 2 people, 8.70%
Enlarged Prostate: 2 people, 8.70%
Urination - Excessive At Night: 1 person, 4.35%

* Approximation only. Some reports may have incomplete information.

Do you take Vesicare and have Sick sinus syndrome?

- Check whether Sick sinus syndrome is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vesicare:

Vesicare (30,656 reports)

Browse all side effects of Vesicare:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sick sinus syndrome:

Sick sinus syndrome (580 drugs)

Browse all the conditions that are associated with Sick sinus syndrome:

Sick sinus syndrome (842 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on solifenacin succinate (the active ingredients of Vesicare) and Vesicare (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.