Vitamin d and Lichen planus - a phase IV clinical study of FDA data

Summary:

Lichen planus is reported as a side effect among people who take Vitamin d (ergocalciferol), especially for people who are female, 60+ old, also take Calcium, and have Herpes zoster.

The phase IV clinical study analyzes which people have Lichen planus when taking Vitamin d. It is created by eHealthMe based on reports of 282,675 people who have side effects when taking Vitamin d from the FDA, and is updated regularly.

What is Vitamin d?

Vitamin d has active ingredients of ergocalciferol. It is often used in low vitamin d. eHealthMe is studying from 294,094 Vitamin d users. Check the latest studies of Vitamin d.

What is Lichen planus?

Lichen planus (an inflammatory skin condition, characterized by an itchy, non-infectious rash) is found to be associated with 249 drugs and 557 conditions by eHealthMe. Check the latest studies of Lichen planus.



On Jul, 25, 2026

282,675 people reported to have side effects when taking Vitamin d.
Among them, 31 people (0.01%) have Lichen planus.

Could Vitamin d cause Lichen planus?

Among these 31 people:

What is the gender of people who have Lichen planus when taking Vitamin d? *

  • female: 82.76 %
  • male: 17.24 %

What is the age of people who have Lichen planus when taking Vitamin d? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 25 %
  • 40-49: 10 %
  • 50-59: 10 %
  • 60+: 55 %

What are other drugs people take besides Vitamin d? *

  1. Calcium: 13 people, 41.94%
  2. Methotrexate: 7 people, 22.58%
  3. Prednisone: 6 people, 19.35%
  4. Zyrtec: 5 people, 16.13%
  5. Dasatinib: 5 people, 16.13%
  6. Cyclosporine: 5 people, 16.13%
  7. Risedronate Sodium: 5 people, 16.13%
  8. Sodium Chloride: 5 people, 16.13%
  9. Humira: 5 people, 16.13%
  10. Prolia: 4 people, 12.90%

What are other side effects people have besides Lichen planus? *

  1. Itching: 11 people, 35.48%
  2. Rashes (redness): 9 people, 29.03%
  3. Drug Ineffective: 6 people, 19.35%
  4. Dry Eyes (lack of adequate tears): 6 people, 19.35%
  5. Lichenification (thickening and hardening of the skin): 5 people, 16.13%
  6. Oral Mucosal Blistering (mouth ulcer): 5 people, 16.13%
  7. Oral Pain: 5 people, 16.13%
  8. Drug Intolerance (drug sensitivity): 5 people, 16.13%
  9. Cytomegalovirus Viraemia (cytomegalo virus in blood stream): 5 people, 16.13%
  10. Rash Maculo-Papular (red area on the skin that is covered with small confluent bumps): 5 people, 16.13%

What are the existing conditions these people have? *

  1. Herpes Zoster: 5 people, 16.13%
  2. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 12.90%
  3. Asthma: 3 people, 9.68%
  4. Osteoporosis Post-Menopausal (weak bone with possibility to break after stopped menstrual cycles): 3 people, 9.68%
  5. Sleep Disorder: 2 people, 6.45%
  6. Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 2 people, 6.45%
  7. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 6.45%
  8. Thyroid Diseases: 2 people, 6.45%
  9. Pain: 2 people, 6.45%
  10. Neurodermatitis (a skin disorder characterized by long lasting itching and scratching): 2 people, 6.45%

* Approximation only. Some reports may have incomplete information.

Do you take Vitamin d and have Lichen planus?

- Check whether Lichen planus is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vitamin d:

Lichen planus treatments and more:

How severe was Lichen planus and when was it recovered:

Expand to all the drugs that have ingredients of ergocalciferol:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vitamin d:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Lichen planus:

Browse all the conditions that are associated with Lichen planus:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ergocalciferol (the active ingredients of Vitamin d) and Vitamin d (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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