Vytorin and Mental disorder - a phase IV clinical study of FDA data

Summary:

Mental disorder is reported as a side effect among people who take Vytorin (ezetimibe; simvastatin), especially for people who are male, 60+ old, have been taking the drug for 2 - 5 years also take Lasix, and have Quit smoking.

The phase IV clinical study analyzes which people have Mental disorder when taking Vytorin. It is created by eHealthMe based on reports of 19,379 people who have side effects when taking Vytorin from the FDA, and is updated regularly.

What is Vytorin?

Vytorin has active ingredients of ezetimibe; simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 20,084 Vytorin users. Check the latest studies of Vytorin.

What is Mental disorder?

Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability) is found to be associated with 1,655 drugs and 1,712 conditions by eHealthMe. Check the latest studies of Mental disorder.



On Jul, 11, 2026

19,379 people reported to have side effects when taking Vytorin.
Among them, 95 people (0.49%) have Mental disorder.

Could Vytorin cause Mental disorder?

Among these 95 people:

How long have people been on Vytorin when they have Mental disorder? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 16.67 %
  • 6 - 12 months: 8.33 %
  • 1 - 2 years: 33.33 %
  • 2 - 5 years: 41.67 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Mental disorder when taking Vytorin? *

  • female: 49.46 %
  • male: 50.54 %

What is the age of people who have Mental disorder when taking Vytorin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 11.76 %
  • 40-49: 16.18 %
  • 50-59: 33.82 %
  • 60+: 38.24 %

What are other drugs people take besides Vytorin? *

  1. Lasix: 18 people, 18.95%
  2. Nexium: 16 people, 16.84%
  3. Coumadin: 15 people, 15.79%
  4. Aspirin: 15 people, 15.79%
  5. Plavix: 14 people, 14.74%
  6. Digoxin: 13 people, 13.68%
  7. Chantix: 13 people, 13.68%
  8. Pantoprazole: 12 people, 12.63%
  9. Crestor: 12 people, 12.63%
  10. Lisinopril: 11 people, 11.58%

What are other side effects people have besides Mental disorder? *

  1. Stress And Anxiety: 45 people, 47.37%
  2. Depression: 44 people, 46.32%
  3. Weakness: 27 people, 28.42%
  4. Pain: 24 people, 25.26%
  5. Memory Loss: 22 people, 23.16%
  6. Suicidal Ideation: 22 people, 23.16%
  7. Chest Pain: 21 people, 22.11%
  8. Confusional State: 18 people, 18.95%
  9. Personality Disorder: 16 people, 16.84%
  10. Fatigue (feeling of tiredness): 16 people, 16.84%

What are the existing conditions these people have? *

  1. Quit Smoking: 15 people, 15.79%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 12 people, 12.63%
  3. Pain: 9 people, 9.47%
  4. Stress And Anxiety: 9 people, 9.47%
  5. Depression: 7 people, 7.37%
  6. Diabetes: 6 people, 6.32%
  7. Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 5 people, 5.26%
  8. Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 4 people, 4.21%
  9. Restless Leg Syndrome (a powerful urge to move your legs): 4 people, 4.21%
  10. Back Pain: 4 people, 4.21%

* Approximation only. Some reports may have incomplete information.

Do you take Vytorin and have Mental disorder?

- Check whether Mental disorder is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vytorin:

Mental disorder treatments and more:

How severe was Mental disorder and when was it recovered:

Expand to all the drugs that have ingredients of ezetimibe; simvastatin:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vytorin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Mental disorder:

Browse all the conditions that are associated with Mental disorder:


How the study uses the data?

The study uses data from the FDA. It is based on ezetimibe; simvastatin (the active ingredients of Vytorin) and Vytorin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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