Vytorin and Temperature intolerance - a phase IV clinical study of FDA data

Summary:

Temperature intolerance is reported as a side effect among people who take Vytorin (ezetimibe; simvastatin), especially for people who are male, 60+ old, have been taking the drug for 1 - 2 years also take Ambien, and have Gait disturbance.

The phase IV clinical study analyzes which people have Temperature intolerance when taking Vytorin. It is created by eHealthMe based on reports of 19,379 people who have side effects when taking Vytorin from the FDA, and is updated regularly.

What is Vytorin?

Vytorin has active ingredients of ezetimibe; simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 20,084 Vytorin users. Check the latest studies of Vytorin.

What is Temperature intolerance?

Temperature intolerance (inability to go in temperature) is found to be associated with 819 drugs and 754 conditions by eHealthMe. Check the latest studies of Temperature intolerance.

On Jul, 25, 2026

19,379 people reported to have side effects when taking Vytorin.
Among them, 14 people (0.07%) have Temperature intolerance.

Could Vytorin cause Temperature intolerance?

Among these 14 people:

How long have people been on Vytorin when they have Temperature intolerance? *

What is the gender of people who have Temperature intolerance when taking Vytorin? *

female: 35.71 %
male: 64.29 %

What is the age of people who have Temperature intolerance when taking Vytorin? *

What are other drugs people take besides Vytorin? *

What are other side effects people have besides Temperature intolerance? *

Fatigue (feeling of tiredness): 6 people, 42.86%
Joint Pain: 5 people, 35.71%
Weakness: 4 people, 28.57%
Atelectasis (partial or complete collapse of the lung): 3 people, 21.43%
Hyperhidrosis (abnormally increased sweating): 3 people, 21.43%
Kidney Stones: 3 people, 21.43%
Acute Kidney Failure: 3 people, 21.43%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 14.29%
Fever: 2 people, 14.29%
Abdominal Fullness Prematurely After Meals: 2 people, 14.29%

What are the existing conditions these people have? *

Gait Disturbance: 2 people, 14.29%
Type 2 Diabetes: 1 person, 7.14%
Hair Disorder: 1 person, 7.14%
Blood Iron Decreased: 1 person, 7.14%
Bone Disorder: 1 person, 7.14%
Cardiac Disorder: 1 person, 7.14%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 1 person, 7.14%
Diabetic Retinal Oedema (excessive build-up of fluid in the retina due to diabetes): 1 person, 7.14%
Glaucoma (increased fluid pressure in the eye with vision loss): 1 person, 7.14%
Growth Hormone Deficiency: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Vytorin and have Temperature intolerance?

- Check whether Temperature intolerance is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vytorin:

Vytorin (20,084 reports)

Browse all side effects of Vytorin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Temperature intolerance:

Temperature intolerance (819 drugs)

Browse all the conditions that are associated with Temperature intolerance:

Temperature intolerance (754 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ezetimibe; simvastatin (the active ingredients of Vytorin) and Vytorin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.