Xigris and Cardiac arrest - a phase IV clinical study of FDA data

Summary:

Cardiac arrest is reported as a side effect among people who take Xigris (drotrecogin alfa (activated)), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Vancomycin, and have Sepsis.

The phase IV clinical study analyzes which people have Cardiac arrest when taking Xigris. It is created by eHealthMe based on reports of 3,539 people who have side effects when taking Xigris from the FDA, and is updated regularly.

What is Xigris?

Xigris has active ingredients of drotrecogin alfa (activated). eHealthMe is studying from 3,542 Xigris users. Check the latest studies of Xigris.

What is Cardiac arrest?

Cardiac arrest is found to be associated with 2,236 drugs and 2,512 conditions by eHealthMe. Check the latest studies of Cardiac arrest.

On Jul, 11, 2026

3,539 people reported to have side effects when taking Xigris.
Among them, 120 people (3.39%) have Cardiac arrest.

Among these 120 people:

* Approximation only. Some reports may have incomplete information.

Do you take Xigris and have Cardiac arrest?

- Check whether Cardiac arrest is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Xigris:

Xigris (3,542 reports)

Cardiac arrest treatments and more:

Cardiac arrest (101,931 reports)

How severe was Cardiac arrest and when was it recovered:

Cardiac arrest in Xigris

Expand to all the drugs that have ingredients of drotrecogin alfa (activated):

Cardiac arrest and drugs with ingredients of drotrecogin alfa (activated)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Xigris:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cardiac arrest:

Cardiac arrest (2,236 drugs)

Browse all the conditions that are associated with Cardiac arrest:

Cardiac arrest (2,512 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on drotrecogin alfa (activated) (the active ingredients of Xigris) and Xigris (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.