Xtandi and Intraocular pressure increased - a phase IV clinical study of FDA data

Summary:

Intraocular pressure increased is reported as a side effect among people who take Xtandi (enzalutamide), especially for people who are male, 60+ old, also take Xgeva, and have Prostate cancer metastatic.

The phase IV clinical study analyzes which people have Intraocular pressure increased when taking Xtandi. It is created by eHealthMe based on reports of 51,433 people who have side effects when taking Xtandi from the FDA, and is updated regularly.

What is Xtandi?

Xtandi has active ingredients of enzalutamide. eHealthMe is studying from 51,498 Xtandi users. Check the latest studies of Xtandi.

What is Intraocular pressure increased?

Intraocular pressure increased is found to be associated with 717 drugs and 954 conditions by eHealthMe. Check the latest studies of Intraocular pressure increased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

51,433 people reported to have side effects when taking Xtandi.
Among them, 19 people (0.04%) have Intraocular pressure increased.

Could Xtandi cause Intraocular pressure increased?

Among these 19 people:

What is the gender of people who have Intraocular pressure increased when taking Xtandi? *

female: 0.0 %
male: 100 %

What is the age of people who have Intraocular pressure increased when taking Xtandi? *

What are other drugs people take besides Xtandi? *

What are other side effects people have besides Intraocular pressure increased? *

Vision Blurred: 12 people, 63.16%
Hyphaema (collection of blood inside the front part of the eye): 11 people, 57.89%
Central Nervous System Lesion (an abnormality in tissue of brain or spinal cord): 10 people, 52.63%
Prostatic Specific Antigen Increased: 10 people, 52.63%
Cyclitis (inflammation of the ciliary body (eye)): 8 people, 42.11%
Pigmentary Glaucoma (affliction of the eye that can lead to a form of glaucoma): 8 people, 42.11%
Lymph Follicular Hypertrophy (an increase in the size of the lymph node follicles): 6 people, 31.58%
Malignant Neoplasm Progression (cancer tumour came back): 6 people, 31.58%
Iridocyclitis (inflammation of the iris and ciliary body of the eye): 6 people, 31.58%
Metastases To Bone (cancer spreads to bone): 4 people, 21.05%

What are the existing conditions these people have? *

Prostate Cancer Metastatic: 11 people, 57.89%
Prostate Cancer: 4 people, 21.05%
Idiopathic Pulmonary Fibrosis (chronic lung disease): 1 person, 5.26%
High Blood Pressure: 1 person, 5.26%
Cough: 1 person, 5.26%
Bone Disorder: 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Xtandi and have Intraocular pressure increased?

- Check whether Intraocular pressure increased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Xtandi:

Xtandi (51,498 reports)

Browse all side effects of Xtandi:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Intraocular pressure increased:

Intraocular pressure increased (717 drugs)

Browse all the conditions that are associated with Intraocular pressure increased:

Intraocular pressure increased (954 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on enzalutamide (the active ingredients of Xtandi) and Xtandi (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.