Yondelis and Appetite - decreased - a phase IV clinical study of FDA data

Summary:

Appetite - decreased is reported as a side effect among people who take Yondelis (trabectedin), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Aloxi, and have Leiomyosarcoma metastatic.

The phase IV clinical study analyzes which people have Appetite - decreased when taking Yondelis. It is created by eHealthMe based on reports of 1,220 people who have side effects when taking Yondelis from the FDA, and is updated regularly.

What is Yondelis?

Yondelis has active ingredients of trabectedin. eHealthMe is studying from 1,220 Yondelis users. Check the latest studies of Yondelis.

What is Appetite - decreased?

Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat) is found to be associated with 3,562 drugs and 4,588 conditions by eHealthMe. Check the latest studies of Appetite - decreased.



On Jul, 11, 2026

1,220 people reported to have side effects when taking Yondelis.
Among them, 38 people (3.11%) have Appetite - decreased.

Could Yondelis cause Appetite - decreased?

Among these 38 people:

How long have people been on Yondelis when they have Appetite - decreased? *

  • < 1 month: 84.62 %
  • 1 - 6 months: 15.38 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Appetite - decreased when taking Yondelis? *

  • female: 61.76 %
  • male: 38.24 %

What is the age of people who have Appetite - decreased when taking Yondelis? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 6.45 %
  • 20-29: 6.45 %
  • 30-39: 3.23 %
  • 40-49: 12.9 %
  • 50-59: 16.13 %
  • 60+: 54.84 %

What are other drugs people take besides Yondelis? *

  1. Aloxi: 5 people, 13.16%
  2. Votrient: 4 people, 10.53%
  3. Decadron: 2 people, 5.26%
  4. Nexium: 2 people, 5.26%
  5. Alprazolam: 1 person, 2.63%
  6. Emend: 1 person, 2.63%
  7. Levothroid: 1 person, 2.63%
  8. Glipizide: 1 person, 2.63%
  9. Fosamax: 1 person, 2.63%
  10. Flovent: 1 person, 2.63%

What are other side effects people have besides Appetite - decreased? *

  1. Nausea (feeling of having an urge to vomit): 21 people, 55.26%
  2. Thrombocytopenia (decrease of platelets in blood): 17 people, 44.74%
  3. Malaise (a feeling of general discomfort or uneasiness): 13 people, 34.21%
  4. White Blood Cell Count Decreased: 11 people, 28.95%
  5. Nausea And Vomiting: 11 people, 28.95%
  6. Alanine Aminotransferase Increased: 11 people, 28.95%
  7. Anaemia (lack of blood): 11 people, 28.95%
  8. Aspartate Aminotransferase Increased: 10 people, 26.32%
  9. Neutrophil Count Decreased (less than normal number of neutrophil a type of blood cell): 9 people, 23.68%
  10. Weight Decreased: 7 people, 18.42%

What are the existing conditions these people have? *

  1. Leiomyosarcoma (a very rare soft tissue sarcoma (cancer) that grows in muscle tissue): 5 people, 13.16%
  2. Leiomyosarcoma Metastatic (a very rare soft tissue sarcoma (cancer) that grows in muscle tissue spreading to other parts): 5 people, 13.16%
  3. Ovarian Cancer (cancer of ovary): 4 people, 10.53%
  4. Rhabdomyosarcoma (cancer of the bone, soft tissues, or connective tissue (e.g., tendon or cartilage)): 4 people, 10.53%
  5. Synovial Sarcoma Metastatic (tumour of synovial membrane of joint spreads to other): 3 people, 7.89%
  6. Liposarcoma (a cancer tumour that arises in fat cells in deep soft tissue): 3 people, 7.89%
  7. Malignant Fibrous Histiocytoma Metastatic (a cancer tumour of uncertain origin that arises both in soft tissue and bone spreads to other part of body): 2 people, 5.26%
  8. Fever: 2 people, 5.26%
  9. Liposarcoma Metastatic (a cancer tumour that arises in fat cells in deep soft tissue spreads to other part): 2 people, 5.26%
  10. Angiosarcoma (cancer of endothelial-type cells that line vessel walls): 2 people, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Yondelis and have Appetite - decreased?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Yondelis:

Appetite - decreased treatments and more:

How severe was Appetite - decreased and when was it recovered:

Expand to all the drugs that have ingredients of trabectedin:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Yondelis:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Appetite - decreased:

Browse all the conditions that are associated with Appetite - decreased:


How the study uses the data?

The study uses data from the FDA. It is based on trabectedin (the active ingredients of Yondelis) and Yondelis (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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