Zanaflex and Multiple sclerosis - a phase IV clinical study of FDA data
Summary:
Multiple sclerosis is reported as a side effect among people who take Zanaflex (tizanidine hydrochloride), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Avonex, and have Relapsing-remitting multiple sclerosis.
The phase IV clinical study analyzes which people have Multiple sclerosis when taking Zanaflex. It is created by eHealthMe based on reports of 16,325 people who have side effects when taking Zanaflex from the FDA, and is updated regularly.
What is Zanaflex?
Zanaflex has active ingredients of tizanidine hydrochloride. It is often used in muscle spasms. eHealthMe is studying from 17,474 Zanaflex users. Check the latest studies of Zanaflex.
What is Multiple sclerosis?
Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath) is found to be associated with 1,130 drugs and 1,347 conditions by eHealthMe. Check the latest studies of Multiple sclerosis.
16,325 people reported to have side effects when taking Zanaflex.
Among them, 390 people (2.39%) have Multiple sclerosis.

Among these 390 people:
How long have people been on Zanaflex when they have Multiple sclerosis? *
What is the gender of people who have Multiple sclerosis when taking Zanaflex? *
What is the age of people who have Multiple sclerosis when taking Zanaflex? *
What are other drugs people take besides Zanaflex? *
What are other side effects people have besides Multiple sclerosis? *
What are the existing conditions these people have? *
* Approximation only. Some reports may have incomplete information.
Do you take Zanaflex and have Multiple sclerosis?
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Related studies:
Effectiveness of, long term effects of, and alternative drugs to Zanaflex:
- Zanaflex (17,474 reports)
Multiple sclerosis treatments and more:
- Multiple sclerosis (799,632 reports)
How severe was Multiple sclerosis and when was it recovered:
Expand to all the drugs that have ingredients of tizanidine hydrochloride:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Common Zanaflex side effects:
- Zanaflex side effect: Fatigue (feeling of tiredness) (1,576 reports)
- Zanaflex side effect: Nausea (feeling of having an urge to vomit) (1,493 reports)
Browse all side effects of Zanaflex:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon drugs associated with Multiple sclerosis:
- Tysabri side effect: Multiple sclerosis (11,991 reports)
- Avonex side effect: Multiple sclerosis (10,786 reports)
- Tecfidera side effect: Multiple sclerosis (6,281 reports)
- Baclofen side effect: Multiple sclerosis (3,874 reports)
- Ampyra side effect: Multiple sclerosis (3,421 reports)
- Ocrevus side effect: Multiple sclerosis (3,365 reports)
- Gilenya side effect: Multiple sclerosis (2,792 reports)
- Copaxone side effect: Multiple sclerosis (2,696 reports)
- Aubagio side effect: Multiple sclerosis (2,444 reports)
- Rebif side effect: Multiple sclerosis (2,403 reports)
Browse all the drugs that are associated with Multiple sclerosis:
- Multiple sclerosis (1,130 drugs)
Common conditions associated with Multiple sclerosis:
- Ms: 28,446 reports
- Multiple sclerosis: 28,330 reports
- Ms hug: 22,414 reports
- Rrms: 3,931 reports
- Gait disturbance: 1,360 reports
- Pain: 1,100 reports
- Alternative medicine - pain relief: 1,092 reports
- Depression: 941 reports
- Antidepressant therapy: 940 reports
- Rheumatoid arthritis: 854 reports
Browse all the conditions that are associated with Multiple sclerosis:
- Multiple sclerosis (1,347 conditions)
Drugs similar to Zanaflex and Multiple sclerosis :
Related publications that referenced our studies
- Christopher KL, Elner VM, Demirci H, "Conjunctival Lymphoma in a Patient on Fingolimod for Relapsing-Remitting Multiple Sclerosis", Ophthalmic Plastic & Reconstructive Surgery, 2017 May .
- Christopher, K. L., Elner, V. M., & Demirci, H. , "Conjunctival lymphoma in a patient on fingolimod for relapsing-remitting multiple sclerosis", Ophthalmic plastic and reconstructive surgery , 2014 Jan .
- Christopher KL, Elner VM, Demirci H, "Conjunctival Lymphoma in a Patient on Fingolimod for Relapsing-Remitting Multiple Sclerosis", Ophthalmic Plastic & Reconstructive Surgery, 2017 May .
- Christopher, K. L., Elner, V. M., & Demirci, H. , "Conjunctival lymphoma in a patient on fingolimod for relapsing-remitting multiple sclerosis", Ophthalmic plastic and reconstructive surgery , 2014 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on tizanidine hydrochloride (the active ingredients of Zanaflex) and Zanaflex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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