Zanaflex and Squamous cell carcinoma of skin - a phase IV clinical study of FDA data

Summary:

Squamous cell carcinoma of skin is reported as a side effect among people who take Zanaflex (tizanidine hydrochloride), especially for people who are male, 60+ old, also take Lyrica, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Squamous cell carcinoma of skin when taking Zanaflex. It is created by eHealthMe based on reports of 16,325 people who have side effects when taking Zanaflex from the FDA, and is updated regularly.

What is Zanaflex?

Zanaflex has active ingredients of tizanidine hydrochloride. It is often used in muscle spasms. eHealthMe is studying from 17,476 Zanaflex users. Check the latest studies of Zanaflex.

What is Squamous cell carcinoma of skin?

Squamous cell carcinoma of skin (a cancer of a kind of epithelial cell, the squamous cell. these cells are the main part of the epidermis of the skin) is found to be associated with 583 drugs and 652 conditions by eHealthMe. Check the latest studies of Squamous cell carcinoma of skin.

On Jul, 15, 2026

16,325 people reported to have side effects when taking Zanaflex.
Among them, 36 people (0.22%) have Squamous cell carcinoma of skin.

Could Zanaflex cause Squamous cell carcinoma of skin?

Among these 36 people:

What is the gender of people who have Squamous cell carcinoma of skin when taking Zanaflex? *

female: 13.89 %
male: 86.11 %

What is the age of people who have Squamous cell carcinoma of skin when taking Zanaflex? *

What are other drugs people take besides Zanaflex? *

What are other side effects people have besides Squamous cell carcinoma of skin? *

Confusional State: 32 people, 88.89%
Back Pain: 30 people, 83.33%
Sleep Disorder: 30 people, 83.33%
Dyspnea (difficult or laboured breathing): 30 people, 83.33%
Bowen's Disease (early stage of skin cancer): 30 people, 83.33%
Blood Immunoglobulin G Increased: 30 people, 83.33%
General Physical Health Deterioration (weak health status): 30 people, 83.33%
Haematuria (presence of blood in urine): 30 people, 83.33%
Hallucinations (sensations that appear real but are created by your mind): 30 people, 83.33%
Multiple Myeloma (cancer of the plasma cells): 30 people, 83.33%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 30 people, 83.33%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 8.33%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 8.33%
Fatigue (feeling of tiredness): 2 people, 5.56%
Osteoporosis (bones weak and more likely to break): 2 people, 5.56%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 2 people, 5.56%
High Blood Pressure: 2 people, 5.56%
Diabetes: 2 people, 5.56%
Constipation: 2 people, 5.56%
Blood Potassium Decreased: 1 person, 2.78%

* Approximation only. Some reports may have incomplete information.

Do you take Zanaflex and have Squamous cell carcinoma of skin?

- Check whether Squamous cell carcinoma of skin is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zanaflex:

Zanaflex (17,476 reports)

Browse all side effects of Zanaflex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Squamous cell carcinoma of skin:

Squamous cell carcinoma of skin (583 drugs)

Browse all the conditions that are associated with Squamous cell carcinoma of skin:

Squamous cell carcinoma of skin (652 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on tizanidine hydrochloride (the active ingredients of Zanaflex) and Zanaflex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.