Zantac and Anoxic encephalopathy - a phase IV clinical study of FDA data

Summary:

Anoxic encephalopathy is reported as a side effect among people who take Zantac (ranitidine hydrochloride), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Folic Acid, and have Epilepsy.

The phase IV clinical study analyzes which people have Anoxic encephalopathy when taking Zantac. It is created by eHealthMe based on reports of 432,014 people who have side effects when taking Zantac from the FDA, and is updated regularly.

What is Zantac?

Zantac has active ingredients of ranitidine hydrochloride. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 434,161 Zantac users. Check the latest studies of Zantac.

What is Anoxic encephalopathy?

Anoxic encephalopathy (brain damage due to lack of oxygen) is found to be associated with 192 drugs and 367 conditions by eHealthMe. Check the latest studies of Anoxic encephalopathy.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

432,014 people reported to have side effects when taking Zantac.
Among them, 24 people (0.01%) have Anoxic encephalopathy.

Could Zantac cause Anoxic encephalopathy?

Among these 24 people:

How long have people been on Zantac when they have Anoxic encephalopathy? *

What is the gender of people who have Anoxic encephalopathy when taking Zantac? *

female: 62.5 %
male: 37.5 %

What is the age of people who have Anoxic encephalopathy when taking Zantac? *

What are other drugs people take besides Zantac? *

What are other side effects people have besides Anoxic encephalopathy? *

Hypotension (abnormally low blood pressure): 12 people, 50.00%
Nausea And Vomiting: 10 people, 41.67%
Cardiac Arrest: 10 people, 41.67%
Fever: 9 people, 37.50%
Tricuspid Valve Incompetence (inefficient heart valve): 9 people, 37.50%
Diarrhea: 9 people, 37.50%
Pulmonary Oedema (fluid accumulation in the lungs): 8 people, 33.33%
Ventricular Hypertrophy (enlargement of ventricles (lower chambers) in the heart): 8 people, 33.33%
Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 8 people, 33.33%
Electrocardiogram Qt Prolonged: 8 people, 33.33%

What are the existing conditions these people have? *

Stress And Anxiety: 7 people, 29.17%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 7 people, 29.17%
Traumatic Haemorrhage (a bleeding due to trauma): 5 people, 20.83%
Breast Cancer: 2 people, 8.33%
Feelings Of Worthlessness: 1 person, 4.17%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1 person, 4.17%

* Approximation only. Some reports may have incomplete information.

Do you take Zantac and have Anoxic encephalopathy?

- Check whether Anoxic encephalopathy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zantac:

Zantac (434,161 reports)

Browse all side effects of Zantac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Anoxic encephalopathy:

Anoxic encephalopathy (192 drugs)

Browse all the conditions that are associated with Anoxic encephalopathy:

Anoxic encephalopathy (367 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ranitidine hydrochloride (the active ingredients of Zantac) and Zantac (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.