Zantac and Breath odor - a phase IV clinical study of FDA data

Summary:

Breath odor is reported as a side effect among people who take Zantac (ranitidine hydrochloride), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Reglan, and have Osteoporosis.

The phase IV clinical study analyzes which people have Breath odor when taking Zantac. It is created by eHealthMe based on reports of 432,014 people who have side effects when taking Zantac from the FDA, and is updated regularly.

What is Zantac?

Zantac has active ingredients of ranitidine hydrochloride. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 434,161 Zantac users. Check the latest studies of Zantac.

What is Breath odor?

Breath odor is found to be associated with 463 drugs and 771 conditions by eHealthMe. Check the latest studies of Breath odor.

On Aug, 10, 2026

432,014 people reported to have side effects when taking Zantac.
Among them, 60 people (0.01%) have Breath odor.

Among these 60 people:

How long have people been on Zantac when they have Breath odor? *

What is the gender of people who have Breath odor when taking Zantac? *

female: 82.76 %
male: 17.24 %

What is the age of people who have Breath odor when taking Zantac? *

What are other drugs people take besides Zantac? *

Zometa: 40 people, 66.67%
Reglan: 40 people, 66.67%
Zofran: 28 people, 46.67%
Chlorhexidine Gluconate: 24 people, 40.00%
Aredia: 23 people, 38.33%
Prilosec: 23 people, 38.33%
Xanax: 22 people, 36.67%
Dilaudid: 22 people, 36.67%
Compazine: 21 people, 35.00%
Oxycontin: 21 people, 35.00%

What are other side effects people have besides Breath odor? *

Dyspnea (difficult or laboured breathing): 44 people, 73.33%
Weight Decreased: 41 people, 68.33%
Stomatitis (inflammation of mucous membrane of mouth): 40 people, 66.67%
Osteonecrosis Of Jaw (death of bone of jaw): 33 people, 55.00%
Swelling Face: 31 people, 51.67%
Periodontal Disease (disease that attacks the gum and bone and around the teeth): 30 people, 50.00%
Hypoaesthesia (reduced sense of touch or sensation): 29 people, 48.33%
Dry Mouth: 29 people, 48.33%
Pain: 28 people, 46.67%
Sialoadenitis (inflammation of a salivary gland): 28 people, 46.67%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 16 people, 26.67%
Metastases To Bone (cancer spreads to bone): 12 people, 20.00%
Pain: 12 people, 20.00%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 8 people, 13.33%
Breast Cancer: 8 people, 13.33%
Fever: 8 people, 13.33%
Oedema (fluid collection in tissue): 8 people, 13.33%
Pneumonia: 8 people, 13.33%
Psychotic Disorder: 8 people, 13.33%
Renal Cell Carcinoma (a kidney cancer): 8 people, 13.33%

* Approximation only. Some reports may have incomplete information.

Do you take Zantac and have Breath odor?

- Check whether Breath odor is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zantac:

Zantac (434,161 reports)

Breath odor treatments and more:

Breath odor (3,848 reports)

Browse all side effects of Zantac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Breath odor:

Breath odor (463 drugs)

Browse all the conditions that are associated with Breath odor:

Breath odor (771 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ranitidine hydrochloride (the active ingredients of Zantac) and Zantac (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.