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Zetia and Lichen planus - a phase IV clinical study of FDA data

Summary:

Lichen planus is reported as a side effect among people who take Zetia (ezetimibe), especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months also take Atenolol, and have Blood cholesterol decreased.

The phase IV clinical study analyzes which people have Lichen planus when taking Zetia. It is created by eHealthMe based on reports of 47,765 people who have side effects when taking Zetia from the FDA, and is updated regularly.

What is Zetia?

Zetia has active ingredients of ezetimibe. It is often used in high blood cholesterol. eHealthMe is studying from 49,113 Zetia users. Check the latest studies of Zetia.

What is Lichen planus?

Lichen planus (an inflammatory skin condition, characterized by an itchy, non-infectious rash) is found to be associated with 249 drugs and 557 conditions by eHealthMe. Check the latest studies of Lichen planus.

On Jul, 15, 2026

47,765 people reported to have side effects when taking Zetia.
Among them, 13 people (0.03%) have Lichen planus.

Could Zetia cause Lichen planus?

Among these 13 people:

How long have people been on Zetia when they have Lichen planus? *

  • < 1 month: 33.33 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 50.0 %
  • 1 - 2 years: 16.67 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Lichen planus when taking Zetia? *

  • female: 81.82 %
  • male: 18.18 %

What is the age of people who have Lichen planus when taking Zetia? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 11.11 %
  • 50-59: 33.33 %
  • 60+: 55.56 %

What are other drugs people take besides Zetia? *

  1. Atenolol: 2 people, 15.38%
  2. Zyrtec: 1 person, 7.69%
  3. Byetta: 1 person, 7.69%
  4. Glucophage: 1 person, 7.69%
  5. Furosemide: 1 person, 7.69%
  6. Etodolac: 1 person, 7.69%
  7. Esomeprazole Magnesium: 1 person, 7.69%
  8. Effexor: 1 person, 7.69%
  9. Dyazide: 1 person, 7.69%
  10. Claritin: 1 person, 7.69%

What are other side effects people have besides Lichen planus? *

  1. Urticaria (rash of round, red welts on the skin that itch intensely): 1 person, 7.69%
  2. Heart Attack: 1 person, 7.69%
  3. Bedridden: 1 person, 7.69%
  4. Depression: 1 person, 7.69%
  5. Discomfort: 1 person, 7.69%
  6. Dysplasia (enlargement of an organ or tissue): 1 person, 7.69%
  7. Gastrointestinal Oedema (excessive build-up of fluid in the gastrointestinal tract tissues): 1 person, 7.69%
  8. Gingivitis (inflammation of gums): 1 person, 7.69%
  9. Itching: 1 person, 7.69%
  10. Sweat Gland Infection: 1 person, 7.69%

What are the existing conditions these people have? *

  1. Type 2 Diabetes: 1 person, 7.69%
  2. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 7.69%
  3. Migraine (headache): 1 person, 7.69%
  4. Low Density Lipoprotein: 1 person, 7.69%
  5. Chest Pain: 1 person, 7.69%
  6. Blood Cholesterol Decreased: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Zetia and have Lichen planus?

- Check whether Lichen planus is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zetia:

Lichen planus treatments and more:

How severe was Lichen planus and when was it recovered:

Expand to all the drugs that have ingredients of ezetimibe:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zetia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Lichen planus:

Browse all the conditions that are associated with Lichen planus:

How the study uses the data?

The study uses data from the FDA. It is based on ezetimibe (the active ingredients of Zetia) and Zetia (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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