Zofran and Clostridium test positive - a phase IV clinical study of FDA data

Summary:

Clostridium test positive is reported as a side effect among people who take Zofran (ondansetron hydrochloride), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Protonix, and have Primary pulmonary hypertension.

The phase IV clinical study analyzes which people have Clostridium test positive when taking Zofran. It is created by eHealthMe based on reports of 93,713 people who have side effects when taking Zofran from the FDA, and is updated regularly.

What is Zofran?

Zofran has active ingredients of ondansetron hydrochloride. It is often used in nausea. eHealthMe is studying from 94,987 Zofran users. Check the latest studies of Zofran.

What is Clostridium test positive?

Clostridium test positive is found to be associated with 297 drugs and 423 conditions by eHealthMe. Check the latest studies of Clostridium test positive.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 31, 2026

93,713 people reported to have side effects when taking Zofran.
Among them, 40 people (0.04%) have Clostridium test positive.

Could Zofran cause Clostridium test positive?

Among these 40 people:

How long have people been on Zofran when they have Clostridium test positive? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Clostridium test positive when taking Zofran? *

  • female: 60 %
  • male: 40 %

What is the age of people who have Clostridium test positive when taking Zofran? *

  • 0-1: 2.78 %
  • 2-9: 2.78 %
  • 10-19: 8.33 %
  • 20-29: 0.0 %
  • 30-39: 2.78 %
  • 40-49: 11.11 %
  • 50-59: 13.89 %
  • 60+: 58.33 %

What are other drugs people take besides Zofran? *

  1. Protonix: 14 people, 35.00%
  2. Proair Hfa: 11 people, 27.50%
  3. Flonase: 11 people, 27.50%
  4. Revatio: 11 people, 27.50%
  5. Ativan: 10 people, 25.00%
  6. Neurontin: 9 people, 22.50%
  7. Vitamin D: 8 people, 20.00%
  8. Pepcid: 8 people, 20.00%
  9. Multivitamin: 8 people, 20.00%
  10. Tylenol: 8 people, 20.00%

What are other side effects people have besides Clostridium test positive? *

  1. Diarrhea: 25 people, 62.50%
  2. Abdominal Pain: 16 people, 40.00%
  3. Pneumonia: 13 people, 32.50%
  4. Dehydration (dryness resulting from the removal of water): 12 people, 30.00%
  5. Malaise (a feeling of general discomfort or uneasiness): 11 people, 27.50%
  6. Dyspnea Exertional: 10 people, 25.00%
  7. Fatigue (feeling of tiredness): 9 people, 22.50%
  8. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 8 people, 20.00%
  9. Haemoglobin Decreased: 8 people, 20.00%
  10. Urinary Tract Infection: 8 people, 20.00%

What are the existing conditions these people have? *

  1. Pain: 6 people, 15.00%
  2. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 6 people, 15.00%
  3. Diarrhea: 5 people, 12.50%
  4. Pulmonary Hypertension (increase in blood pressure in the lung artery): 5 people, 12.50%
  5. High Blood Cholesterol: 4 people, 10.00%
  6. Asthma: 3 people, 7.50%
  7. Back Pain: 3 people, 7.50%
  8. Constipation: 3 people, 7.50%
  9. Dyspnea (difficult or laboured breathing): 3 people, 7.50%
  10. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 7.50%

* Approximation only. Some reports may have incomplete information.

Do you take Zofran and have Clostridium test positive?

- Check whether Clostridium test positive is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zofran:

Clostridium test positive treatments and more:

How severe was Clostridium test positive and when was it recovered:

Expand to all the drugs that have ingredients of ondansetron hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zofran:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Clostridium test positive:

Browse all the conditions that are associated with Clostridium test positive:


How the study uses the data?

The study uses data from the FDA. It is based on ondansetron hydrochloride (the active ingredients of Zofran) and Zofran (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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