Zoloft and Systemic lupus erythematosus - a phase IV clinical study of FDA data
Summary:
Systemic lupus erythematosus is found among people who take Zoloft, especially for people who are female, 50-59 old, have been taking the drug for < 1 month.
The phase IV clinical study analyzes which people take Zoloft and have Systemic lupus erythematosus. It is created by eHealthMe based on reports of 118,546 people who have side effects when taking Zoloft from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.
118,546 people reported to have side effects when taking Zoloft.
Among them, 195 people (0.16%) have Systemic lupus erythematosus.
What is Zoloft?
Zoloft has active ingredients of sertraline hydrochloride. It is often used in depression. eHealthMe is studying from 128,418 Zoloft users for its effectiveness, alternative drugs and more.
What is Systemic lupus erythematosus?
Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue) is found to be associated with 2,030 drugs and 1,375 conditions by eHealthMe.
Number of Zoloft and Systemic lupus erythematosus reports submitted per year:

Time on Zoloft when people have Systemic lupus erythematosus *:
Gender of people who have Systemic lupus erythematosus when taking Zoloft*:
Age of people who have Systemic lupus erythematosus when taking Zoloft *:
Common drugs people take besides Zoloft *:
Common side effects people have besides Systemic lupus erythematosus *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Zoloft and have Systemic lupus erythematosus?
Check whether Systemic lupus erythematosus is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Hania A, "Pyoderma Gangrenosum in a Patient With Systemic Lupus Erythematosus: Case Report", Journal of Medical Cases, 2014 Aug .
- Izgi C, Erdem G, Mansuroglu D, Kurtoglu N, Kara M, Gunesdogdu F, "Severe hypokalemia probably associated with sertraline use", Annals of Pharmacotherapy, 2014 Jan .
- Hu P, Lu L, Hu B, Deng F, Fei WJ, "Cyclophosphamide‐Induced Hypertensive Encephalopathy in a Young Girl With Lupus", The Journal of Clinical Hypertension, 2012 Apr .
Related studies
Alternative drugs to, pros and cons of Zoloft:
- Zoloft (128,418 reports)
Systemic lupus erythematosus treatments and more:
- Systemic lupus erythematosus (52,456 reports)
COVID vaccines that are related to Systemic lupus erythematosus:
- Systemic lupus erythematosus in Moderna COVID Vaccine
- Systemic lupus erythematosus in Pfizer BioNTech Covid Vaccine
- Systemic lupus erythematosus in Johnson and Johnson Covid Vaccine
How severe was Systemic lupus erythematosus and when was it recovered:
Expand to all the drugs that have ingredients of sertraline hydrochloride:
Common drugs associated with Systemic lupus erythematosus:
- Accutane: 240 reports
- Acetaminophen: 105 reports
- Acetylsalicylic acid: 146 reports
- Actemra: 3,746 reports
- Actonel: 108 reports
- Adcirca: 146 reports
- Albuterol: 187 reports
- Alendronate sodium: 925 reports
- Alendronic acid: 357 reports
- Allopurinol: 128 reports
- Alprazolam: 153 reports
- Ambien: 202 reports
- Amlodipine: 317 reports
- Arava: 3,784 reports
- Asacol: 122 reports
- Aspirin: 523 reports
- Atenolol: 202 reports
- Ativan: 166 reports
- Avonex: 248 reports
- Azathioprine: 578 reports
- Baclofen: 150 reports
- Benadryl: 196 reports
- Benlysta: 1,148 reports
- Calcium: 334 reports
- Celebrex: 387 reports
- Cellcept: 362 reports
- Cetirizine hydrochloride: 2,793 reports
- Cimzia: 3,666 reports
- Clonazepam: 200 reports
- Clonidine: 105 reports
- Cortisone acetate: 2,257 reports
- Cosentyx: 255 reports
- Coumadin: 265 reports
- Crestor: 135 reports
- Cyclophosphamide: 162 reports
- Cymbalta: 297 reports
- Desoximetasone: 2,431 reports
- Diazepam: 131 reports
- Diclofenac: 1,052 reports
- Diclofenac sodium: 1,439 reports
- Diovan: 111 reports
- Diphen: 167 reports
- Effexor: 161 reports
- Enbrel: 5,060 reports
- Exidine: 131 reports
- Famotidine: 104 reports
- Fish oil: 114 reports
- Flexeril: 132 reports
- Flonase: 126 reports
- Fluoxetine: 101 reports
- Folic acid: 363 reports
- Forteo: 211 reports
- Fosamax: 3,401 reports
- Furosemide: 307 reports
- Gabapentin: 361 reports
- Humalog: 101 reports
- Humira: 6,804 reports
- Hydramine: 166 reports
- Hydrochlorothiazide: 214 reports
- Hydroxychloroquine sulfate: 3,017 reports
- Ibu: 461 reports
- Ibuprofen: 461 reports
- Imuran: 313 reports
- Keppra: 124 reports
- Kevzara: 351 reports
- Klonopin: 136 reports
- Lamictal: 141 reports
- Lansoprazole: 144 reports
- Lantus: 107 reports
- Lasix: 366 reports
- Leflunomide: 1,376 reports
- Letairis: 209 reports
- Levaquin: 113 reports
- Levothyroxine sodium: 149 reports
- Lexapro: 127 reports
- Lipitor: 294 reports
- Lisinopril: 348 reports
- Lopurin: 128 reports
- Loraz: 147 reports
- Lorazepam: 147 reports
- Losartan: 169 reports
- Lyrica: 606 reports
- Magnesium: 142 reports
- Medrol: 141 reports
- Meloxicam: 138 reports
- Metformin: 255 reports
- Methotrexate: 5,513 reports
- Methotrexate sodium: 825 reports
- Morphine: 136 reports
- Mycophenolate mofetil: 368 reports
- Naproxen: 108 reports
- Neurontin: 239 reports
- Nexium: 398 reports
- Nifedipine: 101 reports
- Norco: 101 reports
- Norvasc: 168 reports
- Nuvaring: 106 reports
- Omeprazole: 517 reports
- Opsumit: 208 reports
- Orencia: 4,038 reports
- Otezla: 137 reports
- Oxycodone: 243 reports
- Oxycontin: 166 reports
- Pantoprazole: 517 reports
- Pantoprazole sodium: 114 reports
- Paracetamol: 457 reports
- Percocet: 186 reports
- Plaquenil: 3,107 reports
- Plavix: 112 reports
- Prednisolone: 637 reports
- Prednisone: 5,856 reports
- Premarin: 267 reports
- Prempro: 119 reports
- Prevacid: 145 reports
- Prilosec: 278 reports
- Profen: 461 reports
- Prolia: 133 reports
- Protonix: 218 reports
- Prozac: 119 reports
- Ramipril: 216 reports
- Ranitidine: 107 reports
- Rebif: 193 reports
- Remicade: 5,413 reports
- Remodulin: 106 reports
- Revatio: 117 reports
- Rituxan: 2,104 reports
- Seroquel: 112 reports
- Sertraline: 121 reports
- Simponi: 3,160 reports
- Simvastatin: 176 reports
- Singulair: 225 reports
- Spironolactone: 133 reports
- Stelara: 796 reports
- Sulfamethoxazole: 122 reports
- Sulfasalazine: 3,143 reports
- Symbicort: 102 reports
- Synthroid: 467 reports
- Tacrolimus: 170 reports
- Tecfidera: 108 reports
- Tegretol: 135 reports
- Topamax: 156 reports
- Topicort: 651 reports
- Topiramate: 103 reports
- Tracleer: 204 reports
- Tramadol: 290 reports
- Tylenol: 451 reports
- Tysabri: 153 reports
- Vicodin: 170 reports
- Vioxx: 211 reports
- Vitamin b12: 177 reports
- Vitamin c: 136 reports
- Vitamin d: 521 reports
- Vitamin d3: 235 reports
- Vitamins: 116 reports
- Voltaren: 109 reports
- Wellbutrin: 164 reports
- Xanax: 300 reports
- Xeljanz: 1,847 reports
- Xeljanz xr: 148 reports
- Xolair: 103 reports
- Xyrem: 204 reports
- Zide: 217 reports
- Zocor: 153 reports
- Zofran: 142 reports
- Zoloft: 195 reports
- Zolpidem: 105 reports
- Zyrtec: 273 reports
All the drugs that are associated with Systemic lupus erythematosus:
- Systemic lupus erythematosus (2,030 drugs)
Common conditions associated with Systemic lupus erythematosus:
- Acid reflux: 291 reports
- Acne: 148 reports
- Acne aggravated: 148 reports
- Acne vulgaris: 147 reports
- Adult hypothyroidism: 170 reports
- Agrypnia: 103 reports
- Alternative medicine - pain relief: 580 reports
- Ankylosing spondylitis: 348 reports
- Antidepressant therapy: 334 reports
- Anxiety: 282 reports
- Anxiety and stress: 281 reports
- Arthralgia: 158 reports
- Arthritis: 197 reports
- Asthma: 231 reports
- Birth control: 198 reports
- Birth control and family planning: 198 reports
- Blood cholesterol abnormal: 276 reports
- Blood cholesterol increased: 276 reports
- Blood pressure - high: 653 reports
- Blood triglycerides abnormal: 276 reports
- Blood triglycerides increased: 267 reports
- Bone and joint pain: 142 reports
- Bronchial asthma: 229 reports
- Cannot sleep: 103 reports
- Can't sleep: 103 reports
- Cataplexy: 101 reports
- Chronic asthma: 229 reports
- Colitis ulcerative: 399 reports
- Contraception: 200 reports
- Crohns: 1,372 reports
- Crohn's disease: 1,372 reports
- Crohns disease: 1,372 reports
- Daytime sleep disorder: 185 reports
- Depression: 354 reports
- Diabetes: 171 reports
- Diabetes mellitus: 171 reports
- Diabetes mellitus management: 171 reports
- Dm: 171 reports
- Dyslipidemia: 267 reports
- Epilepsy: 164 reports
- Feeling uptight: 233 reports
- Fibromyalgia: 218 reports
- Fibromyalgia syndrome: 218 reports
- Fibrositis: 213 reports
- Gastroesophageal reflux disease: 291 reports
- Gastrooesophageal reflux disease: 291 reports
- Gerd: 291 reports
- Granulomatous ileocolitis: 1,372 reports
- Hbp: 653 reports
- Heartburn: 291 reports
- Heartburn - chronic: 282 reports
- Hidradenitis: 118 reports
- High blood cholesterol: 267 reports
- High blood cholesterol and triglycerides: 276 reports
- High blood pressure: 653 reports
- High cholesterol: 276 reports
- Hormone replacement therapy: 128 reports
- Hormone therapy: 128 reports
- Hrt: 128 reports
- Htn: 610 reports
- Hypercholesterolaemia: 276 reports
- Hyperlipidemia: 276 reports
- Hypertension: 663 reports
- Hypothyroid: 170 reports
- Hypothyroidism: 170 reports
- Hypothyroids: 166 reports
- Ileitis: 1,372 reports
- Ileitis aggravated: 1,372 reports
- Insomnia: 103 reports
- Insomnia concerns: 103 reports
- Jitters: 281 reports
- Joint aches: 158 reports
- Joint inflammation: 195 reports
- Joint pain: 158 reports
- Ldl/hdl ratio increased: 276 reports
- Lipoprotein test: 276 reports
- Low thyroid: 170 reports
- Lupus: 2,398 reports
- Lupus erythematosus: 928 reports
- Lupus glomerular disease: 192 reports
- Lupus nephritis: 192 reports
- Migraine: 160 reports
- Migraine aggravated: 148 reports
- Migraines: 158 reports
- Ms: 732 reports
- Ms hug: 768 reports
- Multiple sclerosis: 768 reports
- Myofascial pain syndrome: 218 reports
- Narcolepsy: 185 reports
- Nephritis - lupus: 192 reports
- Osteopenia: 114 reports
- Osteoporosis: 540 reports
- Pain: 585 reports
- Pain relief by acupuncture: 580 reports
- Pimples: 147 reports
- Plaque psoriasis: 868 reports
- Pregnancy: 197 reports
- Preventive health care: 119 reports
- Primary pulmonary hypertension: 458 reports
- Psoriasis: 868 reports
- Psoriatic arthropathy: 707 reports
- Pulmonary arterial hypertension: 458 reports
- Pulmonary hypertension: 305 reports
- Pyrosis: 291 reports
- Ra: 6,782 reports
- Reflux: 282 reports
- Regional enteritis: 1,281 reports
- Rheumatoid arthritis: 6,782 reports
- Sle: 2,398 reports
- Sleep disorder: 126 reports
- Sleeping: 103 reports
- Sleeplessness: 103 reports
- Sleep - too much: 126 reports
- Spondylarthropathy: 348 reports
- Spondylitis: 348 reports
- Sporadic primary pulmonary hypertension: 473 reports
- Stiffness in a joint: 158 reports
- Stress: 281 reports
- Stress and anxiety: 281 reports
- Systemic lupus erythematosus: 1,107 reports
- Uc: 399 reports
- Ulcerative colitis: 399 reports
- Wakefulness: 103 reports
- Zits: 147 reports
All the conditions that are associated with Systemic lupus erythematosus:
- Systemic lupus erythematosus (1,375 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on sertraline hydrochloride (the active ingredients of Zoloft) and Zoloft (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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