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Zolpidem and Pupils unequal - a phase IV clinical study of FDA data

Summary:

Pupils unequal is reported as a side effect among people who take Zolpidem (zolpidem tartrate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Arixtra, and have Cerebral venous thrombosis.

The phase IV clinical study analyzes which people have Pupils unequal when taking Zolpidem. It is created by eHealthMe based on reports of 90,339 people who have side effects when taking Zolpidem from the FDA, and is updated regularly.

What is Zolpidem?

Zolpidem has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 92,696 Zolpidem users. Check the latest studies of Zolpidem.

What is Pupils unequal?

Pupils unequal is found to be associated with 210 drugs and 392 conditions by eHealthMe. Check the latest studies of Pupils unequal.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

90,339 people reported to have side effects when taking Zolpidem.
Among them, 16 people (0.02%) have Pupils unequal.

Could Zolpidem cause Pupils unequal?

Among these 16 people:

How long have people been on Zolpidem when they have Pupils unequal? *

  • < 1 month: 50 %
  • 1 - 6 months: 50 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Pupils unequal when taking Zolpidem? *

  • female: 56.25 %
  • male: 43.75 %

What is the age of people who have Pupils unequal when taking Zolpidem? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 7.14 %
  • 30-39: 0.0 %
  • 40-49: 14.29 %
  • 50-59: 7.14 %
  • 60+: 71.43 %

What are other drugs people take besides Zolpidem? *

  1. Alprazolam: 3 people, 18.75%
  2. Enbrel: 3 people, 18.75%
  3. Arixtra: 3 people, 18.75%
  4. Zyprexa: 2 people, 12.50%
  5. Calcium: 2 people, 12.50%
  6. Hydroxyzine: 2 people, 12.50%
  7. Lansoprazole: 2 people, 12.50%
  8. Lipitor: 2 people, 12.50%
  9. Diazepam: 2 people, 12.50%
  10. Depakote: 2 people, 12.50%

What are other side effects people have besides Pupils unequal? *

  1. High Blood Pressure: 4 people, 25.00%
  2. Malaise (a feeling of general discomfort or uneasiness): 4 people, 25.00%
  3. Unresponsive To Stimuli: 3 people, 18.75%
  4. Confusional State: 3 people, 18.75%
  5. Pain: 3 people, 18.75%
  6. Nausea And Vomiting: 3 people, 18.75%
  7. Dizziness: 3 people, 18.75%
  8. Stress And Anxiety: 3 people, 18.75%
  9. Tremor (trembling or shaking movements in one or more parts of your body): 3 people, 18.75%
  10. Depressed Level Of Consciousness: 3 people, 18.75%

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 12.50%
  2. Cerebral Venous Thrombosis (clot in brains venous blood system): 2 people, 12.50%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 6.25%
  4. Poor Quality Sleep: 1 person, 6.25%
  5. Metastases To Central Nervous System (cancer spreads to central nervous system): 1 person, 6.25%
  6. Itching: 1 person, 6.25%
  7. Depression: 1 person, 6.25%
  8. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 6.25%
  9. Agitation (state of anxiety or nervous excitement): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Zolpidem and have Pupils unequal?

- Check whether Pupils unequal is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zolpidem:

Pupils unequal treatments and more:

How severe was Pupils unequal and when was it recovered:

Expand to all the drugs that have ingredients of zolpidem tartrate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zolpidem:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pupils unequal:

Browse all the conditions that are associated with Pupils unequal:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on zolpidem tartrate (the active ingredients of Zolpidem) and Zolpidem (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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