Zosyn and Hiatal hernia - a phase IV clinical study of FDA data

Summary:

Hiatal hernia is reported as a side effect among people who take Zosyn (piperacillin sodium; tazobactam sodium), especially for people who are female, 60+ old, also take Zometa, and have Metastases to bone.

The phase IV clinical study analyzes which people have Hiatal hernia when taking Zosyn. It is created by eHealthMe based on reports of 10,175 people who have side effects when taking Zosyn from the FDA, and is updated regularly.

What is Zosyn?

Zosyn has active ingredients of piperacillin sodium; tazobactam sodium. It is often used in pneumonia. eHealthMe is studying from 10,236 Zosyn users. Check the latest studies of Zosyn.

What is Hiatal hernia?

Hiatal hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm) is found to be associated with 1,304 drugs and 1,564 conditions by eHealthMe. Check the latest studies of Hiatal hernia.

On Jul, 20, 2026

10,175 people reported to have side effects when taking Zosyn.
Among them, 52 people (0.51%) have Hiatal hernia.

Among these 52 people:

What is the gender of people who have Hiatal hernia when taking Zosyn? *

female: 70.73 %
male: 29.27 %

What is the age of people who have Hiatal hernia when taking Zosyn? *

What are other drugs people take besides Zosyn? *

What are other side effects people have besides Hiatal hernia? *

Back Pain: 37 people, 71.15%
Pain: 36 people, 69.23%
Fever: 34 people, 65.38%
Intervertebral Disc Protrusion (spinal disc protrusion): 34 people, 65.38%
Osteonecrosis Of Jaw (death of bone of jaw): 34 people, 65.38%
Diarrhea: 33 people, 63.46%
Acute Kidney Failure: 32 people, 61.54%
Nausea (feeling of having an urge to vomit): 30 people, 57.69%
Arthropathy: 29 people, 55.77%
Abdominal Pain: 29 people, 55.77%

What are the existing conditions these people have? *

Metastases To Bone (cancer spreads to bone): 18 people, 34.62%
Diabetes: 15 people, 28.85%
Bone Pain: 15 people, 28.85%
Breast Cancer: 15 people, 28.85%
Depression: 15 people, 28.85%
High Blood Pressure: 15 people, 28.85%
Pain: 7 people, 13.46%
Anaemia (lack of blood): 6 people, 11.54%
Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 6 people, 11.54%
Multiple Myeloma (cancer of the plasma cells): 5 people, 9.62%

* Approximation only. Some reports may have incomplete information.

Do you take Zosyn and have Hiatal hernia?

- Check whether Hiatal hernia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zosyn:

Zosyn (10,236 reports)

Hiatal hernia treatments and more:

Hiatal hernia (28,705 reports)

How severe was Hiatal hernia and when was it recovered:

Hiatal hernia in Zosyn

Expand to all the drugs that have ingredients of piperacillin sodium; tazobactam sodium:

Hiatal hernia and drugs with ingredients of piperacillin sodium; tazobactam sodium (66 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zosyn:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hiatal hernia:

Hiatal hernia (1,304 drugs)

Browse all the conditions that are associated with Hiatal hernia:

Hiatal hernia (1,564 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on piperacillin sodium; tazobactam sodium (the active ingredients of Zosyn) and Zosyn (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.