Zyflo cr and Alanine aminotransferase increased - a phase IV clinical study of FDA data

Summary:

Alanine aminotransferase increased is reported as a side effect among people who take Zyflo cr (zileuton), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Zocor, and have Arthritis.

The phase IV clinical study analyzes which people have Alanine aminotransferase increased when taking Zyflo cr. It is created by eHealthMe based on reports of 169 people who have side effects when taking Zyflo cr from the FDA, and is updated regularly.

What is Zyflo cr?

Zyflo cr has active ingredients of zileuton. It is often used in asthma. eHealthMe is studying from 184 Zyflo cr users. Check the latest studies of Zyflo cr.

What is Alanine aminotransferase increased?

Alanine aminotransferase increased is found to be associated with 2,166 drugs and 3,304 conditions by eHealthMe. Check the latest studies of Alanine aminotransferase increased.

On Jul, 12, 2026

169 people reported to have side effects when taking Zyflo cr.
Among them, 11 people (6.51%) have Alanine aminotransferase increased.

Could Zyflo cr cause Alanine aminotransferase increased?

Among these 11 people:

How long have people been on Zyflo cr when they have Alanine aminotransferase increased? *

What is the gender of people who have Alanine aminotransferase increased when taking Zyflo cr? *

female: 50 %
male: 50 %

What is the age of people who have Alanine aminotransferase increased when taking Zyflo cr? *

What are other drugs people take besides Zyflo cr? *

What are other side effects people have besides Alanine aminotransferase increased? *

Aspartate Aminotransferase Increased: 5 people, 45.45%
Blood Creatinine Increased: 2 people, 18.18%
Laboratory Test Abnormal: 1 person, 9.09%
Influenza Like Illness: 1 person, 9.09%
Infectious Mononucleosis (infection usually caused by the epstein-barr virus): 1 person, 9.09%
Headache (pain in head): 1 person, 9.09%
Gamma-Glutamyltransferase Increased: 1 person, 9.09%
Fever: 1 person, 9.09%
Fatigue (feeling of tiredness): 1 person, 9.09%
Drug Ineffective: 1 person, 9.09%

What are the existing conditions these people have? *

Psoriasis (immune-mediated disease that affects the skin): 1 person, 9.09%
High Blood Cholesterol: 1 person, 9.09%
Fluid Retention (an abnormal accumulation of fluid in the blood): 1 person, 9.09%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Zyflo cr and have Alanine aminotransferase increased?

- Check whether Alanine aminotransferase increased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zyflo cr:

Zyflo cr (184 reports)

Browse all side effects of Zyflo cr:

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Browse all the drugs that are associated with Alanine aminotransferase increased:

Alanine aminotransferase increased (2,166 drugs)

Browse all the conditions that are associated with Alanine aminotransferase increased:

Alanine aminotransferase increased (3,304 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on zileuton (the active ingredients of Zyflo cr) and Zyflo cr (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.