Zyrtec-d 12 hour and Weight increased - a phase IV clinical study of FDA data

Summary:

Weight increased is reported as a side effect among people who take Zyrtec-d 12 hour (cetirizine hydrochloride; pseudoephedrine hydrochloride), especially for people who are female, 40-49 old, also take Nexium, and have Pain.

The phase IV clinical study analyzes which people have Weight increased when taking Zyrtec-d 12 hour. It is created by eHealthMe based on reports of 702 people who have side effects when taking Zyrtec-d 12 hour from the FDA, and is updated regularly.

What is Zyrtec-d 12 hour?

Zyrtec-d 12 hour has active ingredients of cetirizine hydrochloride; pseudoephedrine hydrochloride. It is often used in allergies. eHealthMe is studying from 981 Zyrtec-d 12 hour users. Check the latest studies of Zyrtec-d 12 hour.

What is Weight increased?

Weight increased is found to be associated with 2,889 drugs and 3,962 conditions by eHealthMe. Check the latest studies of Weight increased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Jul, 25, 2026

702 people reported to have side effects when taking Zyrtec-d 12 hour.
Among them, 37 people (5.27%) have Weight increased.

Could Zyrtec-d 12 hour cause Weight increased?

Among these 37 people:

What is the gender of people who have Weight increased when taking Zyrtec-d 12 hour? *

female: 97.3 %
male: 2.7 %

What is the age of people who have Weight increased when taking Zyrtec-d 12 hour? *

What are other drugs people take besides Zyrtec-d 12 hour? *

What are other side effects people have besides Weight increased? *

Nausea (feeling of having an urge to vomit): 17 people, 45.95%
Pain: 16 people, 43.24%
Constipation: 10 people, 27.03%
Dizziness: 9 people, 24.32%
High Blood Pressure: 9 people, 24.32%
Headache (pain in head): 9 people, 24.32%
Nausea And Vomiting: 8 people, 21.62%
Gait Disturbance: 8 people, 21.62%
Abdominal Pain Upper: 7 people, 18.92%
Swelling: 7 people, 18.92%

What are the existing conditions these people have? *

Pain: 8 people, 21.62%
High Blood Cholesterol: 7 people, 18.92%
Trigeminal Neuralgia (a painful condition of the nerve responsible for most facial sensation): 6 people, 16.22%
Facial Pain: 6 people, 16.22%
Hypersensitivity: 6 people, 16.22%
Asthma: 6 people, 16.22%
Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands): 5 people, 13.51%
Anaemia (lack of blood): 5 people, 13.51%
High Blood Pressure: 5 people, 13.51%
Multiple Myeloma (cancer of the plasma cells): 5 people, 13.51%

* Approximation only. Some reports may have incomplete information.

Do you take Zyrtec-d 12 hour and have Weight increased?

- Check whether Weight increased is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zyrtec-d 12 hour:

Zyrtec-d 12 hour (981 reports)

Weight increased treatments and more:

Weight increased (279,371 reports)

How severe was Weight increased and when was it recovered:

Weight increased in Zyrtec-d 12 hour

Expand to all the drugs that have ingredients of cetirizine hydrochloride; pseudoephedrine hydrochloride:

Weight increased and drugs with ingredients of cetirizine hydrochloride; pseudoephedrine hydrochloride (1,111 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zyrtec-d 12 hour:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Weight increased:

Weight increased (2,889 drugs)

Browse all the conditions that are associated with Weight increased:

Weight increased (3,962 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on cetirizine hydrochloride; pseudoephedrine hydrochloride (the active ingredients of Zyrtec-d 12 hour) and Zyrtec-d 12 hour (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.