Zyrtec and Basedow's disease - a phase IV clinical study of FDA data

Summary:

Basedow's disease is reported as a side effect among people who take Zyrtec (cetirizine hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Methimazole, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Basedow's disease when taking Zyrtec. It is created by eHealthMe based on reports of 109,528 people who have side effects when taking Zyrtec from the FDA, and is updated regularly.

What is Zyrtec?

Zyrtec has active ingredients of cetirizine hydrochloride. It is often used in allergies. eHealthMe is studying from 114,620 Zyrtec users. Check the latest studies of Zyrtec.

What is Basedow's disease?

Basedow's disease (autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones) is found to be associated with 325 drugs and 429 conditions by eHealthMe. Check the latest studies of Basedow's disease.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

109,528 people reported to have side effects when taking Zyrtec.
Among them, 34 people (0.03%) have Basedow's disease.

Among these 34 people:

How long have people been on Zyrtec when they have Basedow's disease? *

What is the gender of people who have Basedow's disease when taking Zyrtec? *

female: 91.18 %
male: 8.82 %

What is the age of people who have Basedow's disease when taking Zyrtec? *

What are other drugs people take besides Zyrtec? *

What are other side effects people have besides Basedow's disease? *

Rashes (redness): 17 people, 50.00%
Oral Pain: 15 people, 44.12%
Nasal Septum Deviation (deviated nasal septum): 15 people, 44.12%
Osteoporosis (bones weak and more likely to break): 15 people, 44.12%
Osteopenia (a condition where bone mineral density is lower than normal): 15 people, 44.12%
Osteomyelitis (infection of bone): 15 people, 44.12%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 15 people, 44.12%
Oral Disorder (mouth disease): 15 people, 44.12%
Computerised Tomogram Abnormal: 15 people, 44.12%
Diplopia (double vision): 15 people, 44.12%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 15 people, 44.12%
Urticaria Pigmentosa (skin disease that produces patches of darker skin (lesions) and very bad itching): 13 people, 38.24%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 7 people, 20.59%
Hyperthyroidism (over activity of the thyroid gland): 3 people, 8.82%
Hiv Infection: 3 people, 8.82%
Weakness: 1 person, 2.94%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 2.94%
Depression: 1 person, 2.94%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 2.94%
Hepatitis C: 1 person, 2.94%

* Approximation only. Some reports may have incomplete information.

Do you take Zyrtec and have Basedow's disease?

- Check whether Basedow's disease is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zyrtec:

Zyrtec (114,620 reports)

Browse all side effects of Zyrtec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Basedow's disease:

Basedow's disease (325 drugs)

Browse all the conditions that are associated with Basedow's disease:

Basedow's disease (429 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on cetirizine hydrochloride (the active ingredients of Zyrtec) and Zyrtec (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.