Zyrtec and Primary myelofibrosis - a phase IV clinical study of FDA data

Summary:

Primary myelofibrosis is reported as a side effect among people who take Zyrtec (cetirizine hydrochloride), especially for people who are female, 50-59 old, have been taking the drug for 1 - 6 months also take Jakafi, and have Polycythaemia vera.

The phase IV clinical study analyzes which people have Primary myelofibrosis when taking Zyrtec. It is created by eHealthMe based on reports of 109,528 people who have side effects when taking Zyrtec from the FDA, and is updated regularly.

What is Zyrtec?

Zyrtec has active ingredients of cetirizine hydrochloride. It is often used in allergies. eHealthMe is studying from 114,619 Zyrtec users. Check the latest studies of Zyrtec.

What is Primary myelofibrosis?

Primary myelofibrosis (primary disorder of the bone marrow) is found to be associated with 324 drugs and 840 conditions by eHealthMe. Check the latest studies of Primary myelofibrosis.

On Jul, 14, 2026

109,528 people reported to have side effects when taking Zyrtec.
Among them, 20 people (0.02%) have Primary myelofibrosis.

Could Zyrtec cause Primary myelofibrosis?

Among these 20 people:

How long have people been on Zyrtec when they have Primary myelofibrosis? *

What is the gender of people who have Primary myelofibrosis when taking Zyrtec? *

female: 90 %
male: 10 %

What is the age of people who have Primary myelofibrosis when taking Zyrtec? *

What are other drugs people take besides Zyrtec? *

Jakafi: 13 people, 65.00%
Ambien: 8 people, 40.00%
Vitamin D3: 6 people, 30.00%
Lisinopril And Hydrochlorothiazide: 5 people, 25.00%
Lisinopril: 5 people, 25.00%
Flexeril: 5 people, 25.00%
Coenzyme Q10: 5 people, 25.00%
Levaquin: 5 people, 25.00%
Folic Acid: 5 people, 25.00%
Armour Thyroid: 5 people, 25.00%

What are other side effects people have besides Primary myelofibrosis? *

Fatigue (feeling of tiredness): 10 people, 50.00%
Nausea (feeling of having an urge to vomit): 9 people, 45.00%
Anaemia (lack of blood): 9 people, 45.00%
Dyspnea (difficult or laboured breathing): 9 people, 45.00%
Dizziness: 8 people, 40.00%
Temperature Intolerance (inability to go in temperature): 8 people, 40.00%
Aquagenic Pruritus (aquagenic pruritis knows what it's like to have such intense itching that we feel we'll lose our minds): 6 people, 30.00%
Splenomegaly (enlargement of spleen): 6 people, 30.00%
White Blood Cell Count Increased: 5 people, 25.00%
Muscle Spasms (muscle contraction): 5 people, 25.00%

What are the existing conditions these people have? *

Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 11 people, 55.00%
High Blood Pressure: 9 people, 45.00%
Essential Thrombocythaemia (chronic blood cancer): 5 people, 25.00%
Itching: 5 people, 25.00%
Hypersensitivity: 4 people, 20.00%
Back Pain: 4 people, 20.00%
Depression: 4 people, 20.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 20.00%
Stress And Anxiety: 4 people, 20.00%
Cardiac Failure Congestive: 4 people, 20.00%

* Approximation only. Some reports may have incomplete information.

Do you take Zyrtec and have Primary myelofibrosis?

- Check whether Primary myelofibrosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zyrtec:

Zyrtec (114,619 reports)

Browse all side effects of Zyrtec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Primary myelofibrosis:

Primary myelofibrosis (324 drugs)

Browse all the conditions that are associated with Primary myelofibrosis:

Primary myelofibrosis (840 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on cetirizine hydrochloride (the active ingredients of Zyrtec) and Zyrtec (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.