Benadryl preservative free vs. Abilify: side effect and effectiveness comparison (a real world drug study)
Summary:
We compare the side effects and drug effectiveness of Benadryl preservative free and Abilify. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 349,567 people who take Benadryl preservative free and Abilify, and is updated regularly.
What is Benadryl preservative free?
Benadryl preservative free has active ingredients of diphenhydramine hydrochloride. It is often used in allergies. eHealthMe is studying from 53 Benadryl preservative free users. Check the latest studies of Benadryl preservative free.
What is Abilify?
Abilify has active ingredients of aripiprazole. It is often used in depression. eHealthMe is studying from 101,456 Abilify users. Check the latest studies of Abilify.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
349,567 people who take Benadryl preservative free and Abilify are studied.

Drugs being compared in this study:
- Benadryl Preservative Free (diphenhydramine hydrochloride)
- Abilify (aripiprazole)
Most common side effects of the drugs, overall:
Most common side effects of the drugs, in long term (1+ years) use:
Drug effectiveness:
Benadryl Preservative Free:
- not at all: 2.88 %
- somewhat: 23.82 %
- moderate: 35.76 %
- high: 28.05 %
- very high: 9.49 %
Abilify:
- not at all: 8.68 %
- somewhat: 23.83 %
- moderate: 28.68 %
- high: 26.0 %
- very high: 12.8 %
Want to compare Benadryl preservative free with Abilify?
- Personalize this study to your gender and age (0-99+)How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Related publications that referenced our studies
- Cetin, M., Celik, M., Cakici, M., Polat, M., & Suner, A, "Aripiprazole-Induced Hoarseness", Turk Psikiyatri Dergisi, 2018 Jan .
- Cetin M, Celik M, Cakici M, Polat M, Suner A, "Aripiprazole induced non-cardiogenic pulmonary edema: a case report", Turk Psikiyatri Dergisi, 2014 Dec .
- Cetin, M., Celik, M., Cakici, M., Polat, M., & Suner, A, "Aripiprazole-Induced Hoarseness", Turk Psikiyatri Dergisi, 2018 Jan .
- Cetin M, Celik M, Cakici M, Polat M, Suner A, "Aripiprazole induced non-cardiogenic pulmonary edema: a case report", Turk Psikiyatri Dergisi, 2014 Dec .
Related studies
Alternative drugs to, pros and cons of:
- Benadryl preservative free
- Abilify (97,320 reports)
Browse all side effects of Benadryl preservative free:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Abilify:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study is based on diphenhydramine hydrochloride and aripiprazole (the active ingredients of Benadryl preservative free and Abilify, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Abdominal Discomfort and Aortic Dilatation - now
- Could Acetaminophen And Hydrocodone Bitartrate cause Metabolic Acidosis? - 2 seconds ago
- Impaired Gastric Emptying and Muscle Spasms - 3 seconds ago
- Could Varenicline Tartrate cause Aggression? - 4 seconds ago
- Drug interactions of Lamotrigine and Prochlorperazine - 6 seconds ago
- Could Acetaminophen And Hydrocodone Bitartrate cause High Blood Cholesterol? - 7 seconds ago
- Hair Loss and Enteritis - 8 seconds ago
- Drug interactions of Naproxen and Optimark - 8 seconds ago
- Could Gaviscon cause Angioedema? - 9 seconds ago
- Drug interactions of Metformin and Nourianz - 16 seconds ago