Promethazine and Sumatriptan drug interactions for women aged 50-59 (a phase IV clinical study of FDA data)

Summary:

Drug interactions are found for women aged 50-59 who take Promethazine (promethazine hydrochloride) and Sumatriptan (sumatriptan succinate) together. We list drug interactions by the duration when the drugs are taken. This phase IV study is created by eHealthMe based on reports of 87 people from the FDA, and is updated regularly.



On Jun, 17, 2026

87 women aged 50-59 who take Promethazine, Sumatriptan and have drug interactions are studied.


What is Promethazine?

Promethazine has active ingredients of promethazine hydrochloride. It is often used in nausea. eHealthMe is studying from 32,300 Promethazine users. Check the latest studies of Promethazine.

What is Sumatriptan?

Sumatriptan has active ingredients of sumatriptan succinate. It is often used in migraine. eHealthMe is studying from 18,159 Sumatriptan users. Check the latest studies of Sumatriptan.

Number of reports submitted per year:

Promethazine and Sumatriptan drug interactions in women aged 50-59.

Most common drug interactions over time *:

< 1 month:

  1. Alopecia (absence of hair from areas of the body)
  2. Hair colour changes
  3. Hair disorder
  4. Suicide attempt

1 - 6 months:

  1. Alopecia (absence of hair from areas of the body)
  2. Hair colour changes
  3. Hair disorder

6 - 12 months:

  1. Alopecia (absence of hair from areas of the body)
  2. Hair colour changes
  3. Hair disorder
  4. Cystitis (inflammation of the wall of the bladder)
  5. Neuropathy peripheral (surface nerve damage)

1 - 2 years:

n/a

2 - 5 years:

  1. Alopecia (absence of hair from areas of the body)
  2. Hair colour changes
  3. Hair disorder

5 - 10 years:

  1. Fibromyalgia (a long-term condition which causes pain all over the body)
  2. Fluid imbalance (imbalance of fluid in body in intake and fluid lost)
  3. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  4. Loss of consciousness
  5. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  6. Osteoporosis (bones weak and more likely to break)
  7. Pain
  8. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  9. Pulmonary mass
  10. Rib fracture

10+ years:

  1. Anxiety
  2. Joint swelling
  3. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  4. Surgery

not specified:

  1. Asthma
  2. Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
  3. Drug hypersensitivity
  4. Feeling hot
  5. Foot fracture
  6. Influenza
  7. Infusion site haemorrhage (bleeding from infusion site)
  8. Injection site warmth
  9. Limb discomfort (discomfort in leg)
  10. Maculopathy (a condition or disease of the macula, the small spot in the retina where vision is keenest)

* Approximation only. Some reports may have incomplete information.

Do you take Promethazine and Sumatriptan?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.



Related publications that referenced our studies:

Related studies:

How the study uses the data?

The study is based on (applicable) gender, age, promethazine hydrochloride and sumatriptan succinate (the active ingredients of Promethazine and Sumatriptan, respectively), and Promethazine and Sumatriptan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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