Flonase and Drowsiness for Women aged 60+ (a phase IV clinical study of FDA data)

Summary:

Drowsiness is found for women aged 60+ who take Flonase (fluticasone propionate). This study is created by eHealthMe based on reports of 13,500 women aged 60+ from the FDA, and is updated regularly. The information that eHealthMe analyzes includes:

Time on Flonase when people have Drowsiness
Top conditions
Top co-used drugs
Top other side effects

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Jul, 30, 2026

13,500 women aged 60+ reported to have side effects when taking Flonase.
Among them, 297 people (2.2%) have Drowsiness

What is Flonase?

Flonase has active ingredients of fluticasone propionate. It is often used in allergies. eHealthMe is studying from 75,441 Flonase users. Check the latest studies of Flonase.

What is Drowsiness?

Drowsiness is found to be associated with 2,864 drugs and 4,800 conditions by eHealthMe. Check the latest studies of Drowsiness.

Number of reports submitted per year:

Could Flonase cause Drowsiness in women aged 60+?

Time on Flonase when people have Drowsiness *

Severity of Drowsiness

n/a

How people recovered from Drowsiness

n/a

Top conditions involved for these people *:

You may use this to check any potential undetected conditions.

Pain: 45 people, 15.15%
Hypersensitivity: 38 people, 12.79%
Fibromyalgia (a long-term condition which causes pain all over the body): 28 people, 9.43%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 19 people, 6.40%
Stress And Anxiety: 19 people, 6.40%
Asthma: 18 people, 6.06%
Depression: 18 people, 6.06%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 17 people, 5.72%
Osteoporosis (bones weak and more likely to break): 16 people, 5.39%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 15 people, 5.05%

Top co-used drugs for these people *:

You may use this to check any potential interacting drugs.

Top other side effects for these people *:

You may use this to check any potential undetected side effects.

Fatigue (feeling of tiredness): 113 people, 38.05%
Dizziness: 67 people, 22.56%
Weakness: 58 people, 19.53%
Nausea (feeling of having an urge to vomit): 58 people, 19.53%
Dyspnea (difficult or laboured breathing): 51 people, 17.17%
Pain: 46 people, 15.49%
Headache (pain in head): 42 people, 14.14%
Diarrhea: 38 people, 12.79%
Insomnia (sleeplessness): 37 people, 12.46%
Feeling Abnormal: 36 people, 12.12%

* Approximation only. Some reports may have incomplete information.

Do you take Flonase and have Drowsiness?

- Check whether Drowsiness is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Related publications that referenced our studies:

Lehrer, S., & Rheinstein, P. H. , "Alzheimer’s Disease and Intranasal Fluticasone Propionate in the FDA MedWatch Adverse Events Database", Journal of Alzheimer's disease reports, (Preprint), 1-5., 2018 Jan .
Lehrer, S., & Rheinstein, P. H. , "Alzheimer’s Disease and Intranasal Fluticasone Propionate in the FDA MedWatch Adverse Events Database", Journal of Alzheimer's disease reports, (Preprint), 1-5., 2018 Jan .

Related studies:

Flonase and Drowsiness

How the study uses the data?

The study is based on (applicable) gender, age, fluticasone propionate (the active ingredients of Flonase) and Flonase (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.