Personalized prediction for a 57 year old woman who takes Melatonin, Estrogel, Levothyroxine Thyroid, Progesterone (an AI-powered real world drug study)

Summary:

This is a personalized prediction of potential side effects and undetected conditions for up to one year, if you would have adverse effects. The study is created by eHealthMe based on data from the FDA.


On Sep, 24, 2025, 6,964,716 related reports were analyzed:

What are the drugs?

What are the conditions?


Potential side effects:

Diarrhea
  • 6.55% for females aged 57 (±5) who have hypothyroidism and jet lag
  • 6.38% for females aged 57 (±5) who have hot flashes and hypothyroidism
  • 5.88% for females aged 57 (±5) who have sleep issues and hypothyroidism
  • 5.02% for females aged 57 (±5) who have hot flashes and jet lag
Dizziness
  • 7.35% for females aged 57 (±5) who have hypothyroidism and jet lag
  • 7.0% for females aged 57 (±5) who have hot flashes and hypothyroidism
  • 6.49% for females aged 57 (±5) who have sleep issues and hypothyroidism
  • 5.23% for females aged 57 (±5) who have sleep issues and jet lag
  • 5.12% for females aged 57 (±5) who have hot flashes and sleep issues
Drug ineffective
  • 16.0% for females aged 57 (±5) who have hot flashes and jet lag
  • 12.62% for females aged 57 (±5) who have hot flashes and sleep issues
  • 11.92% for females aged 57 (±5) who have sleep issues and jet lag
  • 9.25% for females aged 57 (±5) who have sleep issues and hypothyroidism
  • 8.23% for females aged 57 (±5) who have hot flashes and hypothyroidism
  • 7.04% for females aged 57 (±5) who have hypothyroidism and jet lag
  • 6.17% for females aged 57 (±5) who take melatonin
  • 6.17% for females aged 57 (±5) who take progesterone
  • 6.17% for females aged 57 (±5) who take estrogel
  • 6.17% for females aged 57 (±5) who take levothyroxine thyroid
Dyspnea
  • 5.5% for females aged 57 (±5) who have sleep issues and hypothyroidism
  • 5.39% for females aged 57 (±5) who have hypothyroidism and jet lag
  • 5.08% for females aged 57 (±5) who have hot flashes and hypothyroidism
  • 5.0% for females aged 57 (±5) who have sleep issues and jet lag
Fatigue
  • 11.4% for females aged 57 (±5) who have hypothyroidism and jet lag
  • 10.99% for females aged 57 (±5) who have hot flashes and hypothyroidism
  • 9.55% for females aged 57 (±5) who have sleep issues and hypothyroidism
  • 7.89% for females aged 57 (±5) who have hot flashes and jet lag
  • 7.29% for females aged 57 (±5) who have hot flashes and sleep issues
  • 7.15% for females aged 57 (±5) who have sleep issues and jet lag
  • 6.13% for females aged 57 (±5) who take levothyroxine thyroid
  • 6.13% for females aged 57 (±5) who take progesterone
  • 6.13% for females aged 57 (±5) who take melatonin
  • 6.13% for females aged 57 (±5) who take estrogel
Headache
  • 9.04% for females aged 57 (±5) who have hypothyroidism and jet lag
  • 8.72% for females aged 57 (±5) who have hot flashes and hypothyroidism
  • 8.27% for females aged 57 (±5) who have sleep issues and hypothyroidism
  • 7.15% for females aged 57 (±5) who have sleep issues and jet lag
  • 7.12% for females aged 57 (±5) who have hot flashes and sleep issues
  • 6.85% for females aged 57 (±5) who have hot flashes and jet lag
  • 5.27% for females aged 57 (±5) who take levothyroxine thyroid
  • 5.27% for females aged 57 (±5) who take progesterone
  • 5.27% for females aged 57 (±5) who take melatonin
  • 5.27% for females aged 57 (±5) who take estrogel
Hot flush
  • 9.34% for females aged 57 (±5) who have hot flashes and jet lag
Insomnia
  • 9.75% for females aged 57 (±5) who have sleep issues and jet lag
  • 9.29% for females aged 57 (±5) who have hot flashes and sleep issues
  • 7.36% for females aged 57 (±5) who have sleep issues and hypothyroidism
  • 6.78% for females aged 57 (±5) who have hot flashes and jet lag
  • 5.55% for females aged 57 (±5) who have hot flashes and hypothyroidism
  • 5.35% for females aged 57 (±5) who have hypothyroidism and jet lag
Joint pain
  • 6.28% for females aged 57 (±5) who have hypothyroidism and jet lag
  • 6.09% for females aged 57 (±5) who have hot flashes and hypothyroidism
  • 5.48% for females aged 57 (±5) who have sleep issues and hypothyroidism
  • 5.17% for females aged 57 (±5) who have hot flashes and jet lag
Malaise
  • 5.13% for females aged 57 (±5) who have hypothyroidism and jet lag
Nausea
  • 8.19% for females aged 57 (±5) who have hypothyroidism and jet lag
  • 8.06% for females aged 57 (±5) who have hot flashes and hypothyroidism
  • 7.93% for females aged 57 (±5) who have sleep issues and hypothyroidism
  • 7.43% for females aged 57 (±5) who have sleep issues and jet lag
  • 7.42% for females aged 57 (±5) who have hot flashes and sleep issues
  • 7.2% for females aged 57 (±5) who have hot flashes and jet lag
  • 6.44% for females aged 57 (±5) who take melatonin
  • 6.44% for females aged 57 (±5) who take progesterone
  • 6.44% for females aged 57 (±5) who take estrogel
  • 6.44% for females aged 57 (±5) who take levothyroxine thyroid
Pain
  • 7.47% for females aged 57 (±5) who have hot flashes and jet lag
  • 6.17% for females aged 57 (±5) who have hot flashes and sleep issues
  • 6.16% for females aged 57 (±5) who have hot flashes and hypothyroidism
  • 5.98% for females aged 57 (±5) who have hypothyroidism and jet lag
  • 5.97% for females aged 57 (±5) who have sleep issues and hypothyroidism
  • 5.88% for females aged 57 (±5) who have sleep issues and jet lag
Stress and anxiety
  • 5.39% for females aged 57 (±5) who have sleep issues and jet lag
  • 5.28% for females aged 57 (±5) who have sleep issues and hypothyroidism
  • 5.09% for females aged 57 (±5) who have hot flashes and sleep issues
  • 5.06% for females aged 57 (±5) who have hypothyroidism and jet lag
Weakness
  • 6.11% for females aged 57 (±5) who have hypothyroidism and jet lag
  • 5.69% for females aged 57 (±5) who have hot flashes and hypothyroidism
  • 5.32% for females aged 57 (±5) who have sleep issues and hypothyroidism

Potential co-existing conditions:

Asthma
  • 5.26% for females aged 57 (±5) who have hypothyroidism and jet lag
Constipation
  • 8.27% for females aged 57 (±5) who have sleep issues and jet lag
  • 7.12% for females aged 57 (±5) who have hot flashes and sleep issues
  • 5.43% for females aged 57 (±5) who have sleep issues and hypothyroidism
Depression
  • 23.38% for females aged 57 (±5) who have sleep issues and jet lag
  • 20.74% for females aged 57 (±5) who have hot flashes and sleep issues
  • 18.33% for females aged 57 (±5) who have sleep issues and hypothyroidism
  • 15.49% for females aged 57 (±5) who have hypothyroidism and jet lag
  • 14.33% for females aged 57 (±5) who have hot flashes and hypothyroidism
  • 7.12% for females aged 57 (±5) who have hot flashes and jet lag
Diabetes
  • 7.52% for females aged 57 (±5) who have hypothyroidism and jet lag
  • 6.88% for females aged 57 (±5) who have hot flashes and hypothyroidism
  • 6.61% for females aged 57 (±5) who have sleep issues and hypothyroidism
  • 5.8% for females aged 57 (±5) who have sleep issues and jet lag
  • 5.32% for females aged 57 (±5) who have hot flashes and sleep issues
Fibromyalgia
  • 5.39% for females aged 57 (±5) who have sleep issues and jet lag
  • 5.0% for females aged 57 (±5) who have hot flashes and sleep issues
Gastroesophageal reflux disease
  • 12.68% for females aged 57 (±5) who have sleep issues and jet lag
  • 11.67% for females aged 57 (±5) who have sleep issues and hypothyroidism
  • 11.66% for females aged 57 (±5) who have hypothyroidism and jet lag
  • 11.61% for females aged 57 (±5) who have hot flashes and sleep issues
  • 10.86% for females aged 57 (±5) who have hot flashes and hypothyroidism
  • 6.05% for females aged 57 (±5) who have hot flashes and jet lag
High blood cholesterol
  • 13.81% for females aged 57 (±5) who have hypothyroidism and jet lag
  • 12.86% for females aged 57 (±5) who have hot flashes and hypothyroidism
  • 11.8% for females aged 57 (±5) who have sleep issues and hypothyroidism
  • 9.88% for females aged 57 (±5) who have sleep issues and jet lag
  • 9.44% for females aged 57 (±5) who have hot flashes and sleep issues
  • 7.24% for females aged 57 (±5) who have hot flashes and jet lag
High blood pressure
  • 26.35% for females aged 57 (±5) who have hypothyroidism and jet lag
  • 24.35% for females aged 57 (±5) who have hot flashes and hypothyroidism
  • 22.44% for females aged 57 (±5) who have sleep issues and hypothyroidism
  • 18.59% for females aged 57 (±5) who have sleep issues and jet lag
  • 17.44% for females aged 57 (±5) who have hot flashes and sleep issues
  • 11.29% for females aged 57 (±5) who have hot flashes and jet lag
Hot flush
  • 100.0% for females aged 57 (±5) who have hot flashes and jet lag
  • 16.65% for females aged 57 (±5) who have hot flashes and sleep issues
  • 13.48% for females aged 57 (±5) who have hot flashes and hypothyroidism
Multiple sclerosis
  • 6.58% for females aged 57 (±5) who take melatonin
  • 6.58% for females aged 57 (±5) who take estrogel
  • 6.58% for females aged 57 (±5) who take levothyroxine thyroid
  • 6.58% for females aged 57 (±5) who take progesterone
Nausea
  • 7.96% for females aged 57 (±5) who have sleep issues and jet lag
  • 6.96% for females aged 57 (±5) who have hot flashes and sleep issues
  • 5.53% for females aged 57 (±5) who have sleep issues and hypothyroidism
Night sweats
  • 9.8% for females aged 57 (±5) who have hot flashes and jet lag
Pain
  • 19.92% for females aged 57 (±5) who have sleep issues and jet lag
  • 17.99% for females aged 57 (±5) who have hot flashes and sleep issues
  • 15.17% for females aged 57 (±5) who have sleep issues and hypothyroidism
  • 12.27% for females aged 57 (±5) who have hypothyroidism and jet lag
  • 11.64% for females aged 57 (±5) who have hot flashes and hypothyroidism
  • 8.23% for females aged 57 (±5) who have hot flashes and jet lag
Rheumatoid arthritis
  • 11.31% for females aged 57 (±5) who take melatonin
  • 11.31% for females aged 57 (±5) who take estrogel
  • 11.31% for females aged 57 (±5) who take levothyroxine thyroid
  • 11.31% for females aged 57 (±5) who take progesterone
  • 11.23% for females aged 57 (±5) who have hypothyroidism and jet lag
  • 10.5% for females aged 57 (±5) who have hot flashes and hypothyroidism
  • 10.02% for females aged 57 (±5) who have sleep issues and hypothyroidism
  • 8.84% for females aged 57 (±5) who have sleep issues and jet lag
  • 8.29% for females aged 57 (±5) who have hot flashes and sleep issues
  • 5.67% for females aged 57 (±5) who have hot flashes and jet lag
Stress and anxiety
  • 19.27% for females aged 57 (±5) who have sleep issues and jet lag
  • 17.07% for females aged 57 (±5) who have hot flashes and sleep issues
  • 12.97% for females aged 57 (±5) who have sleep issues and hypothyroidism
  • 8.88% for females aged 57 (±5) who have hypothyroidism and jet lag
  • 8.47% for females aged 57 (±5) who have hot flashes and hypothyroidism
  • 5.9% for females aged 57 (±5) who have hot flashes and jet lag

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

How the study uses the data?

The study is based on gender, age, active ingredients of any drugs used, and more. Other drugs that have the same active ingredients (e.g. generic drugs) are considered.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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