Accutane and Coreg drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Accutane (isotretinoin) and Coreg (carvedilol). Common drug interactions include depression among females and inflammatory bowel disease among males.

The phase IV clinical study analyzes what interactions people have when they take Accutane and Coreg. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Accutane?

Accutane has active ingredients of isotretinoin. It is often used in acne. eHealthMe is studying from 35,221 Accutane users. Check the latest studies of Accutane.

What is Coreg?

Coreg has active ingredients of carvedilol. It is often used in high blood pressure. eHealthMe is studying from 49,583 Coreg users. Check the latest studies of Coreg.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 17, 2026

11 people who take Accutane and Coreg together, and have interactions are studied.

Accutane and Coreg drug interactions.

What are the common drug interactions of Accutane and Coreg, by gender? *:

female:

  1. Depression
  2. Injury
  3. Colitis ulcerative (inflammation of colon with ulcer)
  4. Inflammatory bowel disease
  5. Lip dry
  6. Lip pain
  7. Colitis microscopic (inflammation of colon with diarrhoea and abdominal cramps)
  8. Confusional state
  9. Dehydration (dryness resulting from the removal of water)
  10. Diarrhoea

male:

  1. Inflammatory bowel disease
  2. Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
  3. Bipolar disorder (mood disorder)
  4. Dizziness
  5. Dyspnoea (difficult or laboured respiration)
  6. Irritability
  7. Myalgia (muscle pain)
  8. Schizophrenia (a mental disorder characterized by a breakdown of thought processes)
  9. Adverse drug reaction
  10. Anticonvulsant drug level increased

What are the common drug interactions of Accutane and Coreg, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Coronary arterial stent insertion
  2. Flushing (the warm, red condition of human skin)
  3. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Colitis ulcerative (inflammation of colon with ulcer)
  2. Inflammatory bowel disease
  3. Dyspnoea (difficult or laboured respiration)
  4. Nausea (feeling of having an urge to vomit)
  5. Vomiting
  6. Weight decreased
  7. Anal fistula
  8. Arthralgia (joint pain)
  9. Aura
  10. Blood sodium decreased

What are the existing conditions these people have? *

  1. High Blood Cholesterol: 2 people, 18.18%
  2. Insomnia (sleeplessness): 2 people, 18.18%
  3. Stress And Anxiety: 1 person, 9.09%
  4. Dementia (madness): 1 person, 9.09%
  5. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 9.09%
  6. Cardiac Failure Congestive: 1 person, 9.09%
  7. Cardiomyopathy (weakening of the heart muscle): 1 person, 9.09%
  8. Chronic Skin Ulcer (long lasting skin ulcer): 1 person, 9.09%
  9. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1 person, 9.09%
  10. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Accutane and Coreg:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Accutane:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Coreg:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Accutane and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Coreg and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on isotretinoin and carvedilol (the active ingredients of Accutane and Coreg, respectively), and Accutane and Coreg (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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