Accutane and Furosemide drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Accutane (isotretinoin) and Furosemide (furosemide). Common drug interactions include pain in extremity among females and inflammatory bowel disease among males.
The phase IV clinical study analyzes what interactions people have when they take Accutane and Furosemide. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.
What is Accutane?
Accutane has active ingredients of isotretinoin. It is often used in acne. eHealthMe is studying from 35,221 Accutane users. Check the latest studies of Accutane.
What is Furosemide?
Furosemide has active ingredients of furosemide. It is often used in fluid retention. eHealthMe is studying from 316,095 Furosemide users. Check the latest studies of Furosemide.
34 people who take Accutane and Furosemide together, and have interactions are studied.

What are the common drug interactions of Accutane and Furosemide, by gender? *:
female:
- Pain in extremity
- Vision blurred
- Vomiting
- Cheilitis (infection of lips)
- Dry eye (lack of adequate tears)
- Fall
- Intestinal haemorrhage (bleeding from intestine)
- Rectal haemorrhage (bleeding from anus)
- Renal impairment (severely reduced kidney function)
- Abdominal discomfort
male:
- Inflammatory bowel disease
- Depression
- Tooth extraction
- Alopecia (absence of hair from areas of the body)
- Anal fissure
- Aphthous stomatitis (mouth ulcer)
- Arthralgia (joint pain)
- Bone disorder
- Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
- Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
What are the common drug interactions of Accutane and Furosemide, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- Blood creatinine increased
- Blood potassium increased
- Blood urea increased
- Carbon dioxide decreased
- Dehydration (dryness resulting from the removal of water)
- Diarrhoea
- Hypophagia (reduced food intake)
- Toothache (tooth pain)
10-19:
- Abdominal pain
- Anxiety
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Atelectasis (partial or complete collapse of the lung)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Cardiac failure congestive
- Colitis ulcerative (inflammation of colon with ulcer)
- Colonic polyp (extra part of colon tissue grow in intestine)
- Death
- Depression
20-29:
- Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
- Depression
- Emotional distress
- Inflammatory bowel disease
- Intestinal obstruction
- Abdominal pain
- Anaemia (lack of blood)
- Epistaxis (bleed from the nose)
- Haematemesis (vomiting of blood)
- Nausea (feeling of having an urge to vomit)
30-39:
- Depression
- Inflammatory bowel disease
- Irritable bowel syndrome
- Anaemia (lack of blood)
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
- Suicidal ideation
- Headache (pain in head)
- Injury
- Rectal polyp (fleshy growth occurring on the lining of the colon)
40-49:
- Colitis ulcerative (inflammation of colon with ulcer)
- Depression
- Hypotension (abnormally low blood pressure)
- Inflammatory bowel disease
- Injury
- Pericardial effusion (fluid around the heart)
- Pulmonary tuberculosis (lungs tuberculosis)
50-59:
- Hepatitis a antibody positive
- Hepatitis b core antibody positive
- Hepatitis c
- Hepatitis e
- Liver injury
- Asthma
- Colitis ulcerative (inflammation of colon with ulcer)
- Erythema nodosum (skin inflammation that results in reddish, painful, tender lumps most commonly located in the front of the legs below)
- Gastrointestinal injury (injury to gastrointestinal tract)
- Oral herpes (viral infection of mouth)
60+:
- Inflammatory bowel disease
- Depression
- Epistaxis (bleed from the nose)
- Suicidal ideation
- Pain in extremity
- Vision blurred
- Fall
- Impaired healing
- Injury
- Osteonecrosis (death of bone)
What are the existing conditions these people have? *
- High Blood Pressure: 9 people, 26.47%
- High Blood Cholesterol: 5 people, 14.71%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 11.76%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 11.76%
- Stress And Anxiety: 3 people, 8.82%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 8.82%
- Osteoporosis (bones weak and more likely to break): 3 people, 8.82%
- Bone Density Decreased: 3 people, 8.82%
- Psoriasis (immune-mediated disease that affects the skin): 2 people, 5.88%
- Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 5.88%
* Approximation only. Some reports may have incomplete information.
Do you take Accutane and Furosemide?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Accutane (35,221 reports)
- Furosemide (316,095 reports)
Browse all drug interactions of Accutane and Furosemide:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Accutane:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Furosemide:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Accutane and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Furosemide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Ersoy MA, Ersoy HT, "Manic symptoms associated with isotretinoin and methylphenidate combination: a case report", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2014 Sep .
- Ochoa PS, Fisher T, "A 7‐Year Case of Furosemide‐Induced Immune Thrombocytopenia", Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 2013 Jul .
- Ersoy MA, Ersoy HT, "Manic symptoms associated with isotretinoin and methylphenidate combination: a case report", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2014 Sep .
- Ochoa PS, Fisher T, "A 7‐Year Case of Furosemide‐Induced Immune Thrombocytopenia", Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 2013 Jul .
How the study uses the data?
The study uses data from the FDA. It is based on isotretinoin and furosemide (the active ingredients of Accutane and Furosemide, respectively), and Accutane and Furosemide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Could Hepsera cause Arrhythmias? - a second ago
- Drug interactions of Prednisone and Eprex - 21 seconds ago
- Could Multivitamin cause Aspartate Aminotransferase Increased? - 45 seconds ago
- Could Saw Palmetto cause Febrile Neutropenia? - 51 seconds ago
- Could Epinephrine cause Hyperglycemia? - a minute ago
- Drug interactions of Digoxin and Geodon - a minute ago
- Drug interactions of Prinivil and Levetiracetam - a minute ago
- Could Naltrexone cause Tinnitus Aggravated? - a minute ago
- Psoriasis and Torticollis - a minute ago
- Could Tysabri cause Wound Dehiscence? - a minute ago