Acetaminophen and codeine phosphate and Remicade drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Acetaminophen and codeine phosphate (acetaminophen; codeine phosphate) and Remicade (infliximab). Common drug interactions include asterixis among females and colon cancer metastatic among males.

The phase IV clinical study analyzes what interactions people have when they take Acetaminophen and codeine phosphate and Remicade. It is created by eHealthMe based on reports of 43 people who take the same drugs from the FDA, and is updated regularly.

What is Acetaminophen and codeine phosphate?

Acetaminophen and codeine phosphate has active ingredients of acetaminophen; codeine phosphate. It is often used in pain. eHealthMe is studying from 3,220 Acetaminophen and codeine phosphate users. Check the latest studies of Acetaminophen and codeine phosphate.

What is Remicade?

Remicade has active ingredients of infliximab. It is often used in crohn's disease. eHealthMe is studying from 224,011 Remicade users. Check the latest studies of Remicade.



On Jul, 08, 2026

43 people who take Acetaminophen and codeine phosphate and Remicade together, and have interactions are studied.

Acetaminophen and codeine phosphate and Remicade drug interactions.

What are the common drug interactions of Acetaminophen And Codeine Phosphate and Remicade, by gender? *:

female:

  1. Asterixis (flapping tremor, or liver flap)
  2. Blood bilirubin increased
  3. Depression
  4. Encephalopathy (functioning of the brain is affected by some agent or condition)
  5. Hepatitis fulminant (life-threatening condition defined by significantly impaired liver function)
  6. Infusion related reaction
  7. Lupus hepatitis (a chronic inflammatory autoimmune disorder that may affect liver tissue)
  8. Transaminases increased
  9. Odynophagia (painful swallowing, in the mouth (oropharynx) or oesophagus)
  10. Pyrexia (fever)

male:

  1. Colon cancer metastatic (cancer of colon spreads to other part of body)
  2. Agitation (state of anxiety or nervous excitement)
  3. Ocular hyperaemia (an abnormally large amount of blood in eye)
  4. Poisoning
  5. Psoriasis (immune-mediated disease that affects the skin)
  6. Renal failure (kidney dysfunction)
  7. Sepsis (a severe blood infection that can lead to organ failure and death)
  8. Somnolence (a state of near-sleep, a strong desire for sleep)
  9. Splenomegaly (enlargement of spleen)
  10. Squamous cell carcinoma (a cancer of a kind of epithelial cell)

What are the common drug interactions of Acetaminophen And Codeine Phosphate and Remicade, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Histoplasmosis (infection caused by breathing in spores of a fungus)
  2. Renal failure (kidney dysfunction)
  3. Sepsis (a severe blood infection that can lead to organ failure and death)
  4. Splenomegaly (enlargement of spleen)
  5. Respiratory failure (inadequate gas exchange by the respiratory system)

40-49:

  1. Depression
  2. Abdominal pain
  3. Headache (pain in head)
  4. Nausea (feeling of having an urge to vomit)
  5. Vomiting
  6. Dyspnoea (difficult or laboured respiration)
  7. Fluid retention (an abnormal accumulation of fluid in the blood)
  8. Weight increased
  9. Anaesthesia
  10. Dysuria (painful or difficult urination)

50-59:

  1. Asterixis (flapping tremor, or liver flap)
  2. Blood bilirubin increased
  3. Encephalopathy (functioning of the brain is affected by some agent or condition)
  4. Hepatitis fulminant (life-threatening condition defined by significantly impaired liver function)
  5. Lupus hepatitis (a chronic inflammatory autoimmune disorder that may affect liver tissue)
  6. Transaminases increased
  7. Alopecia (absence of hair from areas of the body)
  8. Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
  9. Arthralgia (joint pain)
  10. Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)

60+:

  1. Infusion related reaction
  2. Odynophagia (painful swallowing, in the mouth (oropharynx) or oesophagus)
  3. Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
  4. Cytolytic hepatitis (dissolution or destruction of a liver cell)
  5. Pyoderma gangrenosum (ulcerating condition of skin that results in heaped borders with a typical appearance)
  6. Bladder cancer
  7. Bronchial carcinoma (lung cancer)
  8. Death
  9. Hypercalcaemia (elevated calcium (ca+) level in the blood)
  10. Hypokalaemia (low potassium)

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 22 people, 51.16%
  2. Ankylosing Spondylitis (type of arthritis affecting the spine): 5 people, 11.63%
  3. Psoriasis (immune-mediated disease that affects the skin): 3 people, 6.98%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Acetaminophen and codeine phosphate and Remicade:

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Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Acetaminophen and codeine phosphate:

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Browse all side effects of Remicade:

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Browse all interactions between Acetaminophen and codeine phosphate and drugs from A to Z:

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Browse all interactions between Remicade and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; codeine phosphate and infliximab (the active ingredients of Acetaminophen and codeine phosphate and Remicade, respectively), and Acetaminophen and codeine phosphate and Remicade (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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