Acetaminophen and Ultram er drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Acetaminophen (acetaminophen) and Ultram er (tramadol hydrochloride). Common drug interactions include nausea among females and anaemia among males.
The phase IV clinical study analyzes what interactions people have when they take Acetaminophen and Ultram er. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.
What is Acetaminophen?
Acetaminophen has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 183,077 Acetaminophen users. Check the latest studies of Acetaminophen.
What is Ultram er?
Ultram er has active ingredients of tramadol hydrochloride. It is often used in pain. eHealthMe is studying from 1,387 Ultram er users. Check the latest studies of Ultram er.
12 people who take Acetaminophen and Ultram er together, and have interactions are studied.

What are the common drug interactions of Acetaminophen and Ultram Er, by gender? *:
female:
- Nausea (feeling of having an urge to vomit)
- Angina pectoris (chest pain due to ischemia of the heart muscle)
- Ascites (accumulation of fluid in the abdominal cavity)
- Asthenia (weakness)
- Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Cholecystitis (infection of gallbladder)
- Chronic kidney disease
- Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
- Decreased appetite
male:
- Anaemia (lack of blood)
- Chest pain
- Diarrhoea
- Hyperkalaemia (damage to or disease of the kidney)
- Hypertension (high blood pressure)
- Arthralgia (joint pain)
- Neuropathy peripheral (surface nerve damage)
What are the common drug interactions of Acetaminophen and Ultram Er, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Ascites (accumulation of fluid in the abdominal cavity)
- Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
- Cholecystitis (infection of gallbladder)
- Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
- Decreased appetite
- Gallbladder cholesterolosis (accumulation and deposition of cholesterol inside of the)
- Herpes zoster
- Lung disorder (lung disease)
- Migraine (headache)
- Psoriasis (immune-mediated disease that affects the skin)
30-39:
- Anaemia (lack of blood)
- Chest pain
- Hyperkalaemia (damage to or disease of the kidney)
- Hypertension (high blood pressure)
40-49:
n/a
50-59:
n/a
60+:
- Arthralgia (joint pain)
- Asthenia (weakness)
- Neuropathy peripheral (surface nerve damage)
- Pain in extremity
- Renal failure (kidney dysfunction)
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Chronic kidney disease
- Diarrhoea
- Eye pain
- Fatigue (feeling of tiredness)
What are the existing conditions these people have? *
- Stress And Anxiety: 4 people, 33.33%
- Headache (pain in head): 3 people, 25.00%
- Osteoarthritis (a joint disease caused by cartilage loss in a joint): 3 people, 25.00%
- High Blood Pressure: 3 people, 25.00%
- Insomnia (sleeplessness): 2 people, 16.67%
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 16.67%
- Breakthrough Pain: 2 people, 16.67%
- Constipation: 2 people, 16.67%
- Cough: 2 people, 16.67%
- Dry Eyes (lack of adequate tears): 2 people, 16.67%
* Approximation only. Some reports may have incomplete information.
Do you take Acetaminophen and Ultram er?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Acetaminophen (183,077 reports)
- Ultram er (1,387 reports)
Browse all drug interactions of Acetaminophen and Ultram er:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Acetaminophen:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Ultram er:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Acetaminophen and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ultram er and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Mansour HM, "Tramadol and Disseminated Intravascular Coagulopathy: A Case Report", Medicine Science, 2015 Jan .
- Mansour HM, "Tramadol and Disseminated Intravascular Coagulopathy: A Case Report", Medicine Science, 2015 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on acetaminophen and tramadol hydrochloride (the active ingredients of Acetaminophen and Ultram er, respectively), and Acetaminophen and Ultram er (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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