Actimmune and Flonase drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Actimmune (interferon gamma-1b) and Flonase (fluticasone propionate). Common drug interactions include pneumonia among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Actimmune and Flonase. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Actimmune?

Actimmune has active ingredients of interferon gamma-1b. eHealthMe is studying from 1,734 Actimmune users. Check the latest studies of Actimmune.

What is Flonase?

Flonase has active ingredients of fluticasone propionate. It is often used in allergies. eHealthMe is studying from 75,441 Flonase users. Check the latest studies of Flonase.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

17 people who take Actimmune and Flonase together, and have interactions are studied.

Actimmune and Flonase drug interactions.

What are the common drug interactions of Actimmune and Flonase, by gender? *:

female:

Pneumonia
Anaemia (lack of blood)
Arrhythmia (irregular heartbeat)
Thrombocytopenia (decrease of platelets in blood)

male:

Dyspnoea (difficult or laboured respiration)
Hypoxia (low oxygen in tissues)
Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta)
Aortic valve calcification
Asthenia (weakness)
Atelectasis (partial or complete collapse of the lung)
Blood urea increased
Blood urea nitrogen/creatinine ratio increased
Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection)
Bronchitis acute (acute inflammation of the mucous membrane in the bronchial tubes)

What are the common drug interactions of Actimmune and Flonase, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Arrhythmia (irregular heartbeat)
Pneumonia

20-29:

Rhinorrhoea (watery mucus discharge from the nose)

30-39:

n/a

40-49:

n/a

50-59:

Pneumonia
Dyspnoea (difficult or laboured respiration)
Hypoxia (low oxygen in tissues)
Pyrexia (fever)
Rigors (an episode of shaking or exaggerated shivering)
Thrombocytopenia (decrease of platelets in blood)
Acute respiratory failure
Anaemia (lack of blood)
Bronchitis acute (acute inflammation of the mucous membrane in the bronchial tubes)
Cough

60+:

Anaemia (lack of blood)
Drug ineffective
Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chest pain
Contusion (a type of hematoma of tissue in which capillaries)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Dehydration (dryness resulting from the removal of water)
Gastric ulcer haemorrhage (bleeding ulcer of stomach)
Glaucoma (increased fluid pressure in the eye with vision loss)

What are the existing conditions these people have? *

Idiopathic Pulmonary Fibrosis (chronic lung disease): 6 people, 35.29%
Interstitial Lung Disease: 4 people, 23.53%
Chronic Granulomatous Disease (immune system cells are unable to kill some types of bacteria and fungi): 2 people, 11.76%
Ovarian Cancer Recurrent (reoccurrence of ovary cancer): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

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