Acyclovir sodium and Hydroxyzine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Acyclovir sodium (acyclovir sodium) and Hydroxyzine (hydroxyzine hydrochloride). Common drug interactions include chronic obstructive pulmonary disease among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Acyclovir sodium and Hydroxyzine. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Acyclovir sodium?

Acyclovir sodium has active ingredients of acyclovir sodium. eHealthMe is studying from 1,813 Acyclovir sodium users. Check the latest studies of Acyclovir sodium.

What is Hydroxyzine?

Hydroxyzine has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 54,069 Hydroxyzine users. Check the latest studies of Hydroxyzine.

On Jul, 16, 2026

25 people who take Acyclovir sodium and Hydroxyzine together, and have interactions are studied.

Acyclovir sodium and Hydroxyzine drug interactions.

What are the common drug interactions of Acyclovir Sodium and Hydroxyzine, by gender? *:

female:

Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Compression fracture (fracture due to pressure caused by injury)
Constipation
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Depressive symptom
Device failure
Device related infection
Dyspnoea (difficult or laboured respiration)
Fall

male:

Pneumonia
Pain
Dyspnoea (difficult or laboured respiration)
Hallucination, auditory (perceiving sounds without auditory stimulus)
Laryngospasm (an uncontrolled/involuntary muscular contraction of larynx)
Lipodystrophy acquired (a regional loss of subcutaneous adipose tissue which usually starts in the face, extends downward acquired)
Liver disorder (liver diseases)
Multiple injuries
Myalgia (muscle pain)
Nephropathy (damage to or disease of a kidney)

What are the common drug interactions of Acyclovir Sodium and Hydroxyzine, by age (0-1 to 60+)? *:

0-1:

Pneumonia
Hepatic enzyme increased
Femur fracture
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Laryngospasm (an uncontrolled/involuntary muscular contraction of larynx)
Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
Hepatic mass

2-9:

Anaemia (lack of blood)
Circulatory collapse
Epstein-barr virus associated lymphoproliferative disorder (lymphocytes are produced in excessive quantities associated with epstein-barr virus)
Haemorrhage (bleeding)
Histiocytosis haematophagic
Hyperammonaemia
Hyperuricaemia (level of uric acid in the blood that is abnormally high)
Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
Infection
Oedema (fluid collection in tissue)

10-19:

n/a

20-29:

n/a

30-39:

Emotional distress
Pain
Renal failure (kidney dysfunction)
Bone density decreased
Chronic kidney disease
Depression
Nephrogenic anaemia (anaemia due to kidney disease)
Nephropathy (damage to or disease of a kidney)
Osteoporosis (bones weak and more likely to break)
Skeletal injury (bone and supporting muscle injury)

40-49:

Blood glucose increased
Blood osmolarity decreased
Blood triglycerides increased
Blood urea increased
Bone density decreased
Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
Bone neoplasm malignant (cancer of bone)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cataract (clouding of the lens inside the eye)
Costochondritis (chest wall pain)

50-59:

Dyspnoea (difficult or laboured respiration)
Febrile neutropenia (fever with reduced white blood cells)
Gait disturbance
Oropharyngeal blistering (blister of oropharynx)

60+:

Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Anaemia (lack of blood)
Chest pain
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Compression fracture (fracture due to pressure caused by injury)
Constipation
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Depressive symptom
Device failure

What are the existing conditions these people have? *

Hiv Infection: 7 people, 28.00%
Infection: 5 people, 20.00%
Sedation: 4 people, 16.00%
Metastases To Bone (cancer spreads to bone): 4 people, 16.00%
Oropharyngeal Pain: 3 people, 12.00%
Nasopharyngitis (inflammation of the nasopharynx): 3 people, 12.00%
Genital Herpes (herpes infection of genital): 3 people, 12.00%
Asthma: 3 people, 12.00%
Pain: 2 people, 8.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 8.00%

* Approximation only. Some reports may have incomplete information.

Do you take Acyclovir sodium and Hydroxyzine?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously