Adderall and Implanon drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Adderall (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate) and Implanon (etonogestrel). Common drug interactions include weight increased among females.

The phase IV clinical study analyzes what interactions people have when they take Adderall and Implanon. It is created by eHealthMe based on reports of 50 people who take the same drugs from the FDA, and is updated regularly.

What is Adderall?

Adderall has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 64,224 Adderall users. Check the latest studies of Adderall.

What is Implanon?

Implanon has active ingredients of etonogestrel. It is often used in birth control. eHealthMe is studying from 12,479 Implanon users. Check the latest studies of Implanon.



On Jul, 10, 2026

50 people who take Adderall and Implanon together, and have interactions are studied.

Adderall and Implanon drug interactions.

What are the common drug interactions of Adderall and Implanon, by gender? *:

female:

  1. Weight increased
  2. Drug ineffective
  3. Dyspnoea (difficult or laboured respiration)
  4. Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
  5. Metrorrhagia (uterine bleeding at irregular intervals)
  6. Migraine (headache)
  7. Neck pain
  8. Amenorrhoea (absence of a menstrual period in a woman of reproductive age)
  9. Fall
  10. General anaesthesia

male:

n/a

What are the common drug interactions of Adderall and Implanon, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Metrorrhagia (uterine bleeding at irregular intervals)
  2. Blood urine present
  3. Cataract (clouding of the lens inside the eye)
  4. Disease progression
  5. Drug ineffective
  6. Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
  7. Migraine (headache)
  8. Muscle spasticity (tight or stiff muscles and an inability to control those muscles)
  9. Neck pain
  10. Neuropathy peripheral (surface nerve damage)

20-29:

  1. Application site discomfort
  2. Bacterial infection
  3. Colitis ulcerative (inflammation of colon with ulcer)
  4. Crepitations (noises are produced by the rubbing of parts one against the other)
  5. Fatigue (feeling of tiredness)
  6. General anaesthesia
  7. Headache (pain in head)
  8. Hypersomnia (excessive daytime sleepiness (eds))
  9. Implant site cellulitis (skin infection at implant site)
  10. Implant site pain

30-39:

  1. Nightmare (unpleasant dream)
  2. Poor quality sleep

40-49:

n/a

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 27 people, 54.00%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 20 people, 40.00%
  3. Stress And Anxiety: 3 people, 6.00%
  4. Depression: 3 people, 6.00%

* Approximation only. Some reports may have incomplete information.

Do you take Adderall and Implanon?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Adderall and Implanon:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Adderall:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Implanon:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Adderall and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Implanon and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate and etonogestrel (the active ingredients of Adderall and Implanon, respectively), and Adderall and Implanon (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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