Adderall and Indocin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Adderall (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate) and Indocin (indomethacin). Common drug interactions include multiple sclerosis among females and hallucination among males.

The phase IV clinical study analyzes what interactions people have when they take Adderall and Indocin. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Adderall?

Adderall has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 64,224 Adderall users. Check the latest studies of Adderall.

What is Indocin?

Indocin has active ingredients of indomethacin. It is often used in gout. eHealthMe is studying from 4,559 Indocin users. Check the latest studies of Indocin.

On Jul, 09, 2026

15 people who take Adderall and Indocin together, and have interactions are studied.

What are the common drug interactions of Adderall and Indocin, by gender? *:

female:

Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Complex regional pain syndrome (long lasting pain condition most often affecting one of the limbs (arms, legs, hands, or feet))
Nausea (feeling of having an urge to vomit)
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Essential hypertension (primary hypertension)
Hot flush (sudden feelings of heat)
Hypervigilance
Snoring
Weight increased
Abdominal discomfort

male:

Hallucination (an experience involving the perception of something not present)
Substance-induced psychotic disorder
Overdose
Prostatomegaly (enlargement of the prostate)
Red blood cell count increased
Weight decreased
Weight increased
Suicide attempt
Asthenia (weakness)
Blood testosterone increased

What are the common drug interactions of Adderall and Indocin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Somnolence (a state of near-sleep, a strong desire for sleep)

30-39:

Complex regional pain syndrome (long lasting pain condition most often affecting one of the limbs (arms, legs, hands, or feet))
Hallucination (an experience involving the perception of something not present)
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Substance-induced psychotic disorder
Suicide attempt
Drug hypersensitivity
Fibromyalgia (a long-term condition which causes pain all over the body)
Gastric disorder (disease of stomach)
Haematuria (presence of blood in urine)
Hospitalisation

40-49:

Hot flush (sudden feelings of heat)
Abdominal discomfort
Agitation (state of anxiety or nervous excitement)
Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Constipation
Dehydration (dryness resulting from the removal of water)
Dry mouth
Dysstasia (difficulty in standing)
Fungal infection

50-59:

n/a

60+:

Asthenia (weakness)
Blood testosterone increased
Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
Dysuria (painful or difficult urination)
Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Prostatomegaly (enlargement of the prostate)
Red blood cell count increased
Urinary tract infection

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 33.33%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 26.67%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 3 people, 20.00%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 20.00%
Ankylosing Spondylitis (type of arthritis affecting the spine): 2 people, 13.33%
Stress And Anxiety: 2 people, 13.33%
Depression: 2 people, 13.33%
High Blood Cholesterol: 1 person, 6.67%
Back Pain: 1 person, 6.67%
Birth Control: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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