Viagra and Vraylar drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Viagra (sildenafil citrate) and Vraylar (cariprazine hydrochloride). Common drug interactions include anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Viagra and Vraylar. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Viagra?

Viagra has active ingredients of sildenafil citrate. It is often used in erection problems. eHealthMe is studying from 63,865 Viagra users. Check the latest studies of Viagra.

What is Vraylar?

Vraylar has active ingredients of cariprazine hydrochloride. eHealthMe is studying from 6,136 Vraylar users. Check the latest studies of Vraylar.



On Jul, 09, 2026

32 people who take Viagra and Vraylar together, and have interactions are studied.

Viagra and Vraylar drug interactions.

What are the common drug interactions of Viagra and Vraylar, by gender? *:

female:

n/a

male:

  1. Anxiety
  2. Confusional state
  3. Concussion (short loss of normal brain function in response to a head injury)
  4. Contusion (a type of hematoma of tissue in which capillaries)
  5. Dehydration (dryness resulting from the removal of water)
  6. Fall
  7. Headache (pain in head)
  8. Hypercalcaemia (elevated calcium (ca+) level in the blood)
  9. Hyperhidrosis (abnormally increased sweating)
  10. Hypermetabolism (abnormal increase in the body's basal metabolic rate)

What are the common drug interactions of Viagra and Vraylar, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Anxiety
  2. Aspartate aminotransferase increased
  3. Confusional state
  4. Disturbance in attention
  5. Hypercalcaemia (elevated calcium (ca+) level in the blood)
  6. Hyperhidrosis (abnormally increased sweating)
  7. Hypermetabolism (abnormal increase in the body's basal metabolic rate)
  8. Night sweats (sweating in night)
  9. Petit mal epilepsy (absence seizure)
  10. Blood pressure increased

50-59:

  1. Concussion (short loss of normal brain function in response to a head injury)
  2. Contusion (a type of hematoma of tissue in which capillaries)
  3. Dry mouth
  4. Fall
  5. Headache (pain in head)
  6. Injury
  7. Joint injury
  8. Physical assault
  9. Road traffic accident
  10. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)

60+:

  1. Discomfort
  2. Disturbance in attention
  3. Fatigue (feeling of tiredness)
  4. Initial insomnia (feeling of inadequate or poor-quality sleep)
  5. Insomnia (sleeplessness)
  6. Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)
  7. Sleep disorder
  8. Somnolence (a state of near-sleep, a strong desire for sleep)

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 14 people, 43.75%
  2. Pain: 8 people, 25.00%
  3. Hiv Infection: 4 people, 12.50%
  4. Bipolar Disorder (mood disorder): 4 people, 12.50%
  5. Stress And Anxiety: 3 people, 9.38%
  6. Sleep Disorder: 3 people, 9.38%
  7. Tremor (trembling or shaking movements in one or more parts of your body): 2 people, 6.25%
  8. Indigestion: 2 people, 6.25%
  9. High Blood Pressure: 2 people, 6.25%
  10. Extrapyramidal Disorder (involuntary muscle spasms in the face and neck): 2 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Viagra and Vraylar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Viagra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Vraylar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Viagra and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vraylar and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on sildenafil citrate and cariprazine hydrochloride (the active ingredients of Viagra and Vraylar, respectively), and Viagra and Vraylar (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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