Akineton and Profen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Akineton (biperiden hydrochloride) and Profen (ibuprofen). Common drug interactions include altered state of consciousness among females and altered state of consciousness among males.

The phase IV clinical study analyzes what interactions people have when they take Akineton and Profen. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Akineton?

Akineton has active ingredients of biperiden hydrochloride. It is often used in parkinson's disease. eHealthMe is studying from 6,140 Akineton users. Check the latest studies of Akineton.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,311 Profen users. Check the latest studies of Profen.

On Jul, 11, 2026

26 people who take Akineton and Profen together, and have interactions are studied.

What are the common drug interactions of Akineton and Profen, by gender? *:

female:

Altered state of consciousness (altered state of mind)
Suicide attempt
Urticaria (rash of round, red welts on the skin that itch intensely)
Accommodation disorder
Alcoholism (problems with alcohol)
Anxiety
Blood creatine phosphokinase increased
Confusion
Coordination abnormal (abnormal movement)
Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)

male:

Altered state of consciousness (altered state of mind)
Blood creatine phosphokinase increased
Encephalopathy (functioning of the brain is affected by some agent or condition)
Feeling of despair
Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve)
Social avoidant behaviour (avoiding social connection a personality disorder)
Abdominal pain
Anticonvulsant drug level decreased
Cogwheel rigidity (tension in a muscle which gives way in little jerks when the muscle is stretched)
Cough

What are the common drug interactions of Akineton and Profen, by age (0-1 to 60+)? *:

0-1:

Suicide attempt

2-9:

n/a

10-19:

Altered state of consciousness (altered state of mind)
Urticaria (rash of round, red welts on the skin that itch intensely)
Blood creatine phosphokinase increased
Pyrexia (fever)
Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
Pneumonia
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Multiple drug overdose
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Liver disorder (liver diseases)

20-29:

n/a

30-39:

Accommodation disorder
Alcoholism (problems with alcohol)
Anxiety
Confusion
Coordination abnormal (abnormal movement)
Depression
Hallucinations, mixed (sensations that appear real but are created by your mind -mixed)
Nervousness
Poisoning
Abdominal pain

40-49:

Breast cancer
Suicide attempt

50-59:

Mixed liver injury

60+:

Asthenia (weakness)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Hyperkinesia (higher than normal levels of potassium in the circulating blood; associated with kidney failure or sometimes with the use of diuretic drugs)
Hypokinesia (decreased bodily movement)
Melaena (the passage of black, tarry stools)
Mobility decreased (ability to move is reduced)
On and off phenomenon
Pain in extremity
Purpura (purplish discoloration of the skin)
Resting tremor (an involuntary somewhat rhythmic, muscle contraction and relaxation during resting condition)

What are the existing conditions these people have? *

Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 8 people, 30.77%
Suicide Attempt: 2 people, 7.69%
Stress And Anxiety: 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Akineton and Profen?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously