Alogliptin and Protonix drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Alogliptin (alogliptin benzoate) and Protonix (pantoprazole sodium). Common drug interactions include chronic kidney disease among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Alogliptin and Protonix. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Alogliptin?

Alogliptin has active ingredients of alogliptin benzoate. eHealthMe is studying from 1,943 Alogliptin users. Check the latest studies of Alogliptin.

What is Protonix?

Protonix has active ingredients of pantoprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 132,658 Protonix users. Check the latest studies of Protonix.

On Jul, 11, 2026

14 people who take Alogliptin and Protonix together, and have interactions are studied.

Alogliptin and Protonix drug interactions.

What are the common drug interactions of Alogliptin and Protonix, by gender? *:

female:

Chronic kidney disease
Renal failure (kidney dysfunction)
Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
Acute respiratory failure
Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta)
Aortic valve disease
Cardiac failure
Cardiac failure acute
Cardiac failure congestive
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)

male:

Chronic kidney disease
Renal disorder (kidney disease)
Urinary tract infection
Cellulitis (infection under the skin)
Groin infection (infection in groin)
Hepatic infection
Renal failure (kidney dysfunction)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Sepsis (a severe blood infection that can lead to organ failure and death)

What are the common drug interactions of Alogliptin and Protonix, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Leukocytosis (increased white blood cells)
Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
Renal injury (kidney injury)
Renal tubular necrosis (death of kidney tubules)
Sepsis (a severe blood infection that can lead to organ failure and death)
Urinary tract infection
Cellulitis (infection under the skin)
Groin infection (infection in groin)

50-59:

Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)

60+:

Chronic kidney disease
Renal disorder (kidney disease)
Cardiac failure acute
Cardiac failure congestive
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Constipation
Mitral valve incompetence (inefficient heart valve)
Renal failure (kidney dysfunction)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)

What are the existing conditions these people have? *

Pain: 5 people, 35.71%
High Blood Pressure: 5 people, 35.71%
Diabetes: 5 people, 35.71%
High Blood Cholesterol: 4 people, 28.57%
Type 2 Diabetes: 3 people, 21.43%
Nephropathy (damage to or disease of a kidney): 2 people, 14.29%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 2 people, 14.29%
Fluid Retention (an abnormal accumulation of fluid in the blood): 2 people, 14.29%
Diarrhea: 2 people, 14.29%
Anaemia (lack of blood): 2 people, 14.29%

* Approximation only. Some reports may have incomplete information.

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