Trikafta and Seroquel drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Trikafta (elexacaftor, ivacaftor, tezacaftor; ivacaftor) and Seroquel (quetiapine fumarate). Common drug interactions include fatigue among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Trikafta and Seroquel. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.

What is Trikafta?

Trikafta has active ingredients of elexacaftor, ivacaftor, tezacaftor; ivacaftor. eHealthMe is studying from 11,852 Trikafta users. Check the latest studies of Trikafta.

What is Seroquel?

Seroquel has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. eHealthMe is studying from 120,285 Seroquel users. Check the latest studies of Seroquel.

On Jul, 11, 2026

41 people who take Trikafta and Seroquel together, and have interactions are studied.

Trikafta and Seroquel drug interactions.

What are the common drug interactions of Trikafta and Seroquel, by gender? *:

female:

Fatigue (feeling of tiredness)
Anxiety
Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
Pneumonia
Acne (skin problems that cause pimples)
Hypertrichosis (hair growth on the body in an amount considered abnormal)
Lethargy (tiredness)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Panic attack
Rash

male:

Anxiety
Deafness
Fatigue (feeling of tiredness)
Headache (pain in head)
Ill-defined disorder
Rash
Respiratory disorder (respiratory disease)
Somnolence (a state of near-sleep, a strong desire for sleep)
Suicide attempt
Weight decreased

What are the common drug interactions of Trikafta and Seroquel, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Fatigue (feeling of tiredness)
Headache (pain in head)
Respiratory disorder (respiratory disease)
Somnolence (a state of near-sleep, a strong desire for sleep)

30-39:

Pneumonia
Burning sensation
Carbon monoxide poisoning
Deafness
Diarrhoea
Disturbance in attention
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Hyperadrenocorticism (overproduction of cortisol)
Influenza
Oral candidiasis (fungal infection of mouth)

40-49:

Sputum increased
Fall
Fatigue (feeling of tiredness)
Hip fracture
Weight decreased

50-59:

Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
Cystic fibrosis (disease of the secretary glands)
Dehydration (dryness resulting from the removal of water)
Dizziness
Dyspnoea (difficult or laboured respiration)
Oxygen saturation decreased
Pneumonia
Thrombosis (formation of a blood clot inside a blood vessel)

60+:

Confusional state
Memory impairment

What are the existing conditions these people have? *

Cystic Fibrosis (disease of the secretary glands): 32 people, 78.05%
Cystic Fibrosis Lung (fibrosis with cyst in the lung): 5 people, 12.20%
Stress And Anxiety: 4 people, 9.76%
Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 4 people, 9.76%
Depression: 4 people, 9.76%
Insomnia (sleeplessness): 3 people, 7.32%

* Approximation only. Some reports may have incomplete information.

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