Amlodipine and Difluprednate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Amlodipine (amlodipine besylate) and Difluprednate (difluprednate). Common drug interactions include blood pressure fluctuation among females and decreased appetite among males.

The phase IV clinical study analyzes what interactions people have when they take Amlodipine and Difluprednate. It is created by eHealthMe based on reports of 79 people who take the same drugs from the FDA, and is updated regularly.

What is Amlodipine?

Amlodipine has active ingredients of amlodipine besylate. It is often used in high blood pressure. eHealthMe is studying from 354,829 Amlodipine users. Check the latest studies of Amlodipine.

What is Difluprednate?

Difluprednate has active ingredients of difluprednate. eHealthMe is studying from 977 Difluprednate users. Check the latest studies of Difluprednate.

On Jul, 03, 2026

79 people who take Amlodipine and Difluprednate together, and have interactions are studied.

Amlodipine and Difluprednate drug interactions.

What are the common drug interactions of Amlodipine and Difluprednate, by gender? *:

female:

Blood pressure fluctuation
Blood urea increased
Carbon dioxide decreased
Cardiac murmur (an heart sound in valve abnormality)
Chest pain
Cough
Dizziness
Dysuria (painful or difficult urination)
Fluid overload (too much fluid in the blood)
Gangrene (body tissue dies)

male:

Decreased appetite
Pruritus (severe itching of the skin)
Oedema (fluid collection in tissue)
Onychomadesis (a periodic idiopathic shedding of the nails)
Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
Rash
Interstitial lung disease
Cerebral infarction (less blood supply to brain resulting tissue damage)
Constipation
Pneumonitis (inflammation of the walls of the alveoli in the lungs)

What are the common drug interactions of Amlodipine and Difluprednate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Anaemia (lack of blood)
Burning sensation
Eye irritation
Ocular hyperaemia (an abnormally large amount of blood in eye)
Rhinalgia (pain in the nose)
Swelling

50-59:

Haematocrit increased
Haemoglobin decreased
Headache (pain in head)
Hypoxia (low oxygen in tissues)
Influenza
International normalised ratio increased
Malaise (a feeling of general discomfort or uneasiness)
Metastases to bone (cancer spreads to bone)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Oropharyngeal pain

60+:

Rash
Malaise (a feeling of general discomfort or uneasiness)
Gastric ulcer haemorrhage (bleeding ulcer of stomach)
Nail discolouration (change in nail colour)
Nail ridging (nail has raised ridges and is thin and curved inward)
Oedema (fluid collection in tissue)
Onychomadesis (a periodic idiopathic shedding of the nails)
Oedema peripheral (superficial swelling)
Pneumonia
Cardiac failure

What are the existing conditions these people have? *

Rashes (redness): 15 people, 18.99%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 13 people, 16.46%
Diarrhea: 13 people, 16.46%
Constipation: 11 people, 13.92%
Insomnia (sleeplessness): 10 people, 12.66%
Hypocalcaemia (levels of calcium in blood serum are abnormally low): 10 people, 12.66%
Colon Cancer: 8 people, 10.13%
Nausea And Vomiting: 7 people, 8.86%
Pain: 6 people, 7.59%
Itching: 6 people, 7.59%

* Approximation only. Some reports may have incomplete information.

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